2221948-93-0

Name	Bis-PEG17-NHS ester
Synonyms	Bis-PEG17-NHS ester Bis-dPEG17-NHS ester 4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52-Heptadecaoxapentapentacontanedioic acid, 1,55-bis(2,5-dioxo-1-pyrrolidinyl) ester
CAS	2221948-93-0

Molecular Formula	C46 H80 N2 O25
Molar Mass	1061.13
Density	1.25±0.1 g/cm3(Predicted)
Boling Point	921.6±75.0 °C(Predicted)
Storage Condition	2-8°C，干燥，密封
MDL	MFCD21363288
In vitro study	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

biological activity	Bis-PEG17-NHS ester is a PROTAC connection bridge, belonging to PEG and Alkyl/ether. Bis-PEG17-NHS ester can be used to synthesize a series of PROTAC molecules. Bis-PEG17-NHS ester is a degradable (cleavable) ADC link bridge for the synthesis of antibody drug conjugates (ADCs).
target	PEGs Alkyl/ether Cleavable
in vitro study	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Last Update：2024-04-09 20:02:46

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