22225-77-0 - Names and Identifiers
22225-77-0 - Physico-chemical Properties
Molecular Formula | C7H5F2NO3
|
Molar Mass | 189.12 |
Density | 1.384g/cm3 |
Boling Point | 73 °C |
Flash Point | 104.6°C |
Vapor Presure | 0.0363mmHg at 25°C |
Storage Condition | Room Temprature |
Refractive Index | 1.494 |
22225-77-0 - Risk and Safety
Hazard Symbols | Xi - Irritant

|
Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S23 - Do not breathe vapour.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
|
Hazard Class | IRRITANT |
22225-77-0 - Introduction
2-(difluoromethoxy) nitrbenzene is an organic compound with the chemical formula C7H5F2NO3. It is a colorless to light yellow solid with a peculiar odor. The following is a detailed description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless to light yellow solid
-Melting Point: 45-48 ℃
-Boiling point: 165-167 ℃
-Density: 1.448g/cm³
-Solubility: Soluble in organic solvents such as alcohols, ethers and ketones, very slightly soluble in water
-Stability: relatively stable at room temperature, but sensitive to light and heat
Use:
-Chemical synthesis: 2-(difluoromethoxy) nitrbenzene can be used as an intermediate in certain organic syntheses. For example, it can be used in the synthesis of fluorine-containing organic compounds for pharmaceutical research and manufacturing.
-Chemical reaction: The compound can be reduced to difluoromethyl ether, or further functional group conversion through nucleophilic substitution reaction.
Method:
The preparation method of 2-(difluoromethoxy)nitrobenzene is more complicated. A common method is obtained by the reaction of nitric acid and 2-(difluoromethoxy) benzene alcohol. The specific operating conditions and procedures need to be carried out in a chemical laboratory.
Safety Information:
- 2-(difluoromethoxy)nitrobenzene is an organic compound that requires safe operation when used, such as wearing protective gloves, glasses and laboratory clothing.
-It may be toxic to the human body and may be irritating to the respiratory tract, skin and eyes. Avoid direct contact and inhalation of dust or gas.
-During storage and handling, avoid contact with oxidants, strong acids, and strong bases to prevent dangerous chemical reactions.
-Store it in a dry, ventilated place, away from fire and high temperature.
-In the event of a leak or accident, take appropriate emergency measures immediately and follow relevant handling and disposal procedures.
Please note that this compound is only used in a suitable laboratory environment. In practice, follow all safety and chemical laboratory procedures.
Last Update:2024-04-09 19:05:48