22227-25-4

22227-25-4 - Names and Identifiers

Name	3-(Trifluoromethyl)benzoic acid hydrazide
Synonyms	BUTTPARK 301-47 3-(TRIFLUOROMETHYL)BENZHYDRAZIDE 3-(trifluoromethyl)benzohydrazide 3-(TRIFLUOROMETHYL)BENZOHYDRAZIDE 3-(TRIFLUOROMETHYL)BENZOIC ACID HYDRAZIDE 3-(Trifluoromethyl)benzoic acid hydrazide 3-(TRIFLUOROMETHYL)BENZENE-1-CARBOHYDRAZIDE 3-(Trifluoromethyl)benzene-1-carbohydrazide
CAS	22227-25-4
InChI	InChI=1/C8H7F3N2O/c9-8(10,11)6-3-1-2-5(4-6)7(14)13-12/h1-4H,12H2,(H,13,14)

22227-25-4 - Physico-chemical Properties

Molecular Formula	C8H7F3N2O
Molar Mass	204.15
Density	1.356±0.06 g/cm3(Predicted)
Melting Point	111 °C
pKa	11.93±0.10(Predicted)
Storage Condition	Room Temprature
Refractive Index	1.493

22227-25-4 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Hazard Note	Irritant

22227-25-4 - Introduction

3-(Trifluoromethyl)benzoic acid hydrazide is an organic compound with the chemical formula C8H5F3N2O, with a benzoyl hydrazide group and a Trifluoromethyl group in the structure.

The following are some of the properties and uses of this compound:
-Appearance: White to beige crystalline solid.
-Melting point: About 172-175 degrees Celsius.
-Solubility: Soluble in common organic solvents, such as ethanol, ethyl acetate and dichloromethane.
-purpose: 3-(Trifluoromethyl)benzoic acid hydrazide can be used as raw materials and intermediates in organic synthesis. It can be used in the synthesis of fluorine-containing aromatic compounds, such as fluorine-containing oxalic acid derivatives, as well as the synthesis of other drugs, pesticides and materials.

Preparation Method:
3-(Trifluoromethyl)benzoic acid hydrazide can be prepared by reacting 3-trifluoromethylbenzoic acid with hydrazine. The reaction is carried out at normal temperature and under acidic conditions.

Safety Information:
3-(Trifluoromethyl)benzoic acid hydrazide has limited toxicity and hazard data, so the following should be noted when handling and using:
-Avoid inhaling dust or contact with skin, eyes and mouth.
-Wear appropriate protective equipment such as chemical goggles, gloves and protective clothing during operation.
-Operate under reasonable ventilation conditions.
-If necessary, operate in a chemical exhaust cabinet.
-Waste should be disposed of in accordance with local regulations and in accordance with relevant safe practices.

Last Update：2024-04-09 20:49:11