222551-17-9

Name	Adoprazine
Synonyms	SLV313 SLV-313 SLV 313 Adoprazine adoprazine Unii-7snb18Q89d Adoprazine (SLV313) 1-(2,3-Dihydro-1,4-benzodioxin-5-yl)-4-[[5-(4-fluorophenyl)-3-pyridinyl]methyl]piperazine Piperazine, 1-(2,3-dihydro-1,4-benzodioxin-5-yl)-4-[[5-(4-fluorophenyl)-3-pyridinyl]methyl]-
CAS	222551-17-9

Molecular Formula	C24H24FN3O2
Molar Mass	405.46
Density	1.256
Boling Point	565.0±50.0 °C(Predicted)
pKa	6.07±0.10(Predicted)
Storage Condition	-20℃
In vitro study	Adoprazine (SLV313) has high affinity at human recombinant D 2 , D 3 , D 4 , 5-HT 2B , and 5-HT 1A receptors, with pK i s of 8.4, 8.4, 8.0, 7.9 and 9.1, respectively. Adoprazine (SLV313) acts as a high potency dopamine D 2 receptor antagonist and an efficacious serotonin 5-HT 1A receptor agonist, with E max value (% effect of 10 μM 5-HT) of 73 and pK B value of 8.5 .

Last Update：2024-01-02 23:10:35

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CAS: 222551-17-9
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222551-17-9

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