22348-44-3

22348-44-3 - Names and Identifiers

Name	trans-4-(methylamino)cyclohexanol
Synonyms	cis-4-(Methylamino) cis-4-Methylaminocyclohexanol cis-4-Methylamino-cyclohexanol trans-4-(methylamino)cyclohexanol Cyclohexanol, 4-(methylamino)-, cis- cyclohexanol, 4-(methylamino)-, trans-
CAS	22348-38-5 22348-44-3
InChI	InChI=1/C7H15NO/c1-8-6-2-4-7(9)5-3-6/h6-9H,2-5H2,1H3/t6-,7-

22348-44-3 - Physico-chemical Properties

Molecular Formula	C7H15NO
Molar Mass	129.2
Density	0.97g/cm³
Boling Point	211.7°C at 760 mmHg
Flash Point	86.8°C
Vapor Presure	0.0404mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.479

22348-44-3 - Introduction

trans-4-(methylamino)cyclohexanol is an organic compound with the chemical formula CH3NHCH(OH)CH(CH2)3CH3. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: White crystalline solid.
-Melting point: about 83-85°C.
-Solubility: Soluble in water and some organic solvents, such as ethanol and ether.

Use:
-Medicine: trans-4-(methylamino)cyclohexanol is a beta-blocker that can be used to treat cardiovascular diseases such as hypertension, angina and arrhythmia.
-Organic synthesis: The compound can be used in organic synthesis reactions, such as as catalysts or reaction intermediates.

Method:
trans-4-(methylamino)cyclohexanol can be prepared by the following steps:
1. First, Cyclohexanone is reacted with methylamine to obtain trans-4-methylamino cyclohexyl aldehyde.
2. Then, the trans-4-methylamino-cyclohexyl aldehyde is reduced to obtain trans-4-(methylamino)cyclohexanol.

Safety Information:
- trans-4-(methylamino)cyclohexanol should be used and handled in accordance with laboratory safety procedures.
-Avoid contact with skin, eyes and mucous membranes during use.
-Avoid inhaling its dust or vapor, and operate in a well-ventilated environment.
-If exposed or inhaled, rinse immediately with plenty of water and seek medical help.
-During storage, avoid contact with oxidants, strong acids and other harmful substances to avoid danger.
-Store it in a cool, dry place, away from fire and igniting objects.

Last Update：2024-04-09 21:01:54