224785-90-4
Vardenafil hcl trihydrate
CAS: 224785-90-4
Molecular Formula: C23H32N6O4S
224785-90-4 - Names and Identifiers
| Name | Vardenafil hcl trihydrate |
| Synonyms | FADINAF Vardenafil hcl trihydrate VARDENAFIL(SUBJECTTOPATENTFREE) Vardenafil hydrochloride trihydrate VARDENAFILHYDROCHLORIDETRIHYDRATE(SUBJECTTOPATENTFREE) 2-{2-ethoxy-5-[(4-ethylpiperazin-1-yl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one 2-(2-Ethoxy-5-(4-ethylpiperazin-1-yl-1-sulfonyl)phenyl)-5-methyl-7-propyl-3H-imidazo(5,1-f)(1,2,4)triazin-4-one 2-{2-ethoxy-5-[(4-ethylpiperazin-1-yl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one hydrochloride trihydrate 1-[[3-(1,4-Dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]-4-ethyl-piperazine hydrochloride trihydrate |
| CAS | 224785-90-4 |
| EINECS | 607-088-5 |
| InChI | InChI=1/C23H32N6O4S.ClH.3H2O/c1-5-8-20-24-16(4)21-23(30)25-22(26-29(20)21)18-15-17(9-10-19(18)33-7-3)34(31,32)28-13-11-27(6-2)12-14-28;;;;/h9-10,15H,5-8,11-14H2,1-4H3,(H,25,26,30);1H;3*1H2 |
| InChIKey | NOIHTGOGFDFCBN-UHFFFAOYSA-N |
224785-90-4 - Physico-chemical Properties
| Molecular Formula | C23H32N6O4S |
| Molar Mass | 488.6 |
| Density | 1.37 |
| Melting Point | 230-235°C |
| Boling Point | 692.2°C at 760 mmHg |
| Flash Point | 9℃ |
| Water Solubility | 7mg/L at 20℃ |
| Vapor Presure | 0.001Pa at 71.34℃ |
| pKa | 9.86±0.20(Predicted) |
| Storage Condition | Sealed in dry,Store in freezer, under -20°C |
| Physical and Chemical Properties | Melting Point: 230-235°C |
| In vitro study | Vardenafil specifically inhibits the hydrolysis of cGMP by PDE5 with an IC 50 of 0.7 nM. |
224785-90-4 - Risk and Safety
| Risk Codes | R11 - Highly Flammable R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36 - Irritating to the eyes |
| Safety Description | S16 - Keep away from sources of ignition. S36/37 - Wear suitable protective clothing and gloves. |
| UN IDs | UN1230 - class 3 - PG 2 - Methanol, solution |
| WGK Germany | 1 |
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