22490-86-4
3-amino-3-(3-methoxyphenyl)propan-1-ol
CAS: 22490-86-4
Molecular Formula: C10H15NO2
22490-86-4 - Names and Identifiers
| Name | 3-amino-3-(3-methoxyphenyl)propan-1-ol |
| Synonyms | LogP RARECHEM AK ML 0269 Benzenepropanol, γ-amino-3-methoxy- 3-amino-3-(3-methoxyphenyl)propan-1-ol 3-AMINO-3-(3-METHOXY-PHENYL)-PROPAN-1-OL |
| CAS | 22490-86-4 |
| InChI | InChI=1/C10H15NO2/c1-13-9-4-2-3-8(7-9)10(11)5-6-12/h2-4,7,10,12H,5-6,11H2,1H3 |
22490-86-4 - Physico-chemical Properties
| Molecular Formula | C10H15NO2 |
| Molar Mass | 181.23 |
| Density | 1.100±0.06 g/cm3(Predicted) |
| Melting Point | 41-45 °C |
| Boling Point | 105-115 °C(Press: 0.01 Torr) |
| Flash Point | 155.9°C |
| Vapor Presure | 5.14E-05mmHg at 25°C |
| pKa | 14.91±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Sensitive | Irritant |
| Refractive Index | 1.546 |
| MDL | MFCD03412652 |
22490-86-4 - Risk and Safety
| Hazard Class | IRRITANT |
22490-86-4 - Introduction
3-amino-3-(3-methoxyphenyl)propan-1-ol is an organic compound, its chemical structure contains an amino group, a benzene ring and a methoxy group. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless to pale yellow crystalline solid.
-Molecular formula: C11H17NO2
-Molecular weight: 195.26g/mol
-Melting point: About 60-64 ° C
-Boiling point: About 339 ° C
-Solubility: Very little soluble in water, soluble in organic solvents.
Use:
- 3-amino-3-(3-methoxyphenyl)propan-1-ol is an important organic synthesis intermediate, which can be used to synthesize compounds containing this group.
-It can be used in the field of medicine, as an intermediate of certain drugs, such as anti-cancer drugs, hormone drugs, etc.
Method:
- 3-amino-3-(3-methoxyphenyl)propan-1-ol can be synthesized by a variety of methods, and the specific preparation method will vary according to different requirements and conditions. It can usually be obtained by the following steps:
1. 3-aminopropionaldehyde reacts with methoxyphenyl phenol to carry out nucleophilic substitution reaction under alkaline conditions.
2. The reaction product is subjected to appropriate treatment and purification steps to obtain the target product.
Safety Information:
- 3-amino-3-(3-methoxyphenyl)propan-1-ol has limited data on its toxicity and harmfulness, but should generally be considered toxic due to its toxic Group in its chemical structure.
-During the operation, avoid direct contact with skin and eyes, and ensure that the operation place is well ventilated.
-During handling and storage, follow relevant chemical safety practices and avoid contact with strong oxidants and other incompatible substances.
Due to the nature and wide range of uses of chemicals, safe operating procedures should be followed when using and handling, and corresponding protective measures should be evaluated and taken according to the actual situation.
Nature:
-Appearance: Colorless to pale yellow crystalline solid.
-Molecular formula: C11H17NO2
-Molecular weight: 195.26g/mol
-Melting point: About 60-64 ° C
-Boiling point: About 339 ° C
-Solubility: Very little soluble in water, soluble in organic solvents.
Use:
- 3-amino-3-(3-methoxyphenyl)propan-1-ol is an important organic synthesis intermediate, which can be used to synthesize compounds containing this group.
-It can be used in the field of medicine, as an intermediate of certain drugs, such as anti-cancer drugs, hormone drugs, etc.
Method:
- 3-amino-3-(3-methoxyphenyl)propan-1-ol can be synthesized by a variety of methods, and the specific preparation method will vary according to different requirements and conditions. It can usually be obtained by the following steps:
1. 3-aminopropionaldehyde reacts with methoxyphenyl phenol to carry out nucleophilic substitution reaction under alkaline conditions.
2. The reaction product is subjected to appropriate treatment and purification steps to obtain the target product.
Safety Information:
- 3-amino-3-(3-methoxyphenyl)propan-1-ol has limited data on its toxicity and harmfulness, but should generally be considered toxic due to its toxic Group in its chemical structure.
-During the operation, avoid direct contact with skin and eyes, and ensure that the operation place is well ventilated.
-During handling and storage, follow relevant chemical safety practices and avoid contact with strong oxidants and other incompatible substances.
Due to the nature and wide range of uses of chemicals, safe operating procedures should be followed when using and handling, and corresponding protective measures should be evaluated and taken according to the actual situation.
Last Update：2024-04-09 21:04:16
