230955-75-6

230955-75-6 - Names and Identifiers

Name	6-Acetoxy-4-chloro-7-methoxyquinazoline
Synonyms	Gefitinib IMpurity X Gefitinib interMediate V 6-Acetoxy-4-chloro-7-methoxyquinazoline 4-Chloro-6-acetoxy-7-methoxyquinazoline 6-ACETOXY-4-CHLORO-7-METHOXYQUINAZOLINE 4-Chloro-7-methoxyquinazolin-6-yl acetate 4-chloro-7-methoxyquinazolin-6-yl acetate 4-Chloro-7-methoxy-6-quinazolinol 6-acetate 4-Chloro-7-methoxy-6-quinazolinol 6-acetate 6-Quinazolinol, 4-chloro-7-Methoxy-, 6-acetate N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)-N-(3-morpholinopropyl)quinazolin-4-amine
CAS	230955-75-6
EINECS	1308068-626-2
InChI	InChI=1/C11H9ClN2O3/c1-6(15)17-10-3-7-8(4-9(10)16-2)13-5-14-11(7)12/h3-5H,1-2H3

230955-75-6 - Physico-chemical Properties

Molecular Formula	C11H9ClN2O3
Molar Mass	252.65
Density	1.376
Boling Point	364.6±37.0 °C(Predicted)
Flash Point	174.309°C
Vapor Presure	0mmHg at 25°C
pKa	0.50±0.30(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.605
Use	This product is for scientific research only and shall not be used for other purposes.

230955-75-6 - Introduction

It is an organic compound with a molecular formula of C13H10ClNO3 and a molecular weight of 269.68g/mol. The following is a description of its nature, use, preparation and safety information:

Nature:
is a compound with a nitrogen aromatic ring. It is a white or light yellow crystal with a melting point of about 124-125°C. It has good solubility in petroleum ether, ethanol and chloroform.

Use:
It has certain application value in the field of medicine. It is a highly efficient, broad-spectrum antibacterial drug that can be used to prevent and treat some bacterial infections, such as Streptococcus pneumoniae, Staphylococcus aureus, etc. In addition, it may also have some anti-tumor activity, and has obvious inhibitory effect on some tumor cells.

Method:
The preparation of calcium can be carried out by a variety of methods. A common method is to first react O-aminobenzaldehyde with a compound with an alcohol-based functional group, and then convert it to the target product by chlorination and methyl etherification.

Safety Information:
The current understanding of the safety and toxicity data is still relatively limited, so you should pay attention to the corresponding safety measures when using. Wear appropriate protective equipment such as gloves, safety goggles and protective clothing when working in the laboratory. In addition, the compound should be stored in a dry, cool place to avoid contact with oxygen and moisture.

Last Update：2024-04-09 21:54:55