234082-33-8

234082-33-8 - Names and Identifiers

Name	tert-Butyl 4-(4-(ethoxycarbonyl)phenyl)piperazine-1-carboxylate
Synonyms	Ethyl 4-(4-BOC-piperazino)benzoate tert-Butyl 4-(4-(ethoxycarbonyl)phenyl)piperazine-1-carboxylate 1-Piperazinecarboxylic acid, 4-[4-(ethoxycarbonyl)phenyl]-,1,1-dimethylethyl ester
CAS	234082-33-8

234082-33-8 - Physico-chemical Properties

Molecular Formula	C18H26N2O4
Molar Mass	334.41004
Density	1.136±0.06 g/cm3(Predicted)
Boling Point	463.7±40.0 °C(Predicted)
pKa	2.47±0.10(Predicted)

234082-33-8 - Introduction

tert-Butyl 4-(4-(ethoxycarbonyl)phenyl)piperazine-1-carboxylate is an organic compound with the chemical formula C24H34N2O5.

This compound is a white solid at room temperature with a relative molecular mass of 426.54g/mol. Its melting point is about 90-92 degrees Celsius.

tert-Butyl 4-(4-(ethoxycarbonyl)phenyl)piperazine-1-carboxylate is a commonly used organic synthesis intermediate. It is widely used in drug synthesis and organic synthesis reactions. It can be used as a precursor of an antitumor drug, a receptor-blocking compound, a precursor of a molecule having biological activity, etc. It plays an important role in organic synthesis because of its efficient functional group protection.

The method for preparing tert-Butyl 4-(4-(ethoxycarbonyl)phenyl)piperazine-1-carboxylate is to react p-Toluic acid with piperazine in an appropriate solvent, and then add Yum alcohol (tert-butanol) for alcoholization reaction, and finally add ethyl chloroformate (ethyl chloroformate) for esterification reaction.

Regarding safety information, since tert-Butyl 4-(4-(ethoxycarbonyl)phenyl)piperazine-1-carboxylate is a chemical reagent, it needs to be handled and stored correctly. It is toxic and irritating to the eyes, skin and respiratory system. Appropriate protective equipment, such as chemical goggles, protective gloves and protective face masks, should be worn during use. When stored, should be away from fire and high temperature, stored in a dry, cool place. At the same time, pay attention to prevent contact with oxidants and strong acids to avoid dangerous reactions. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical examination.

In summary, tert-Butyl 4-(4-(ethoxycarbonyl)phenyl)piperazine-1-carboxylate is a commonly used organic synthesis intermediate with a wide range of applications. However, the use of the need to comply with the correct operating practices, and pay attention to safety matters.

Last Update：2024-04-09 21:11:58