2360851-29-0
RBN012759
CAS: 2360851-29-0
Molecular Formula: C19H23FN2O3S
2360851-29-0 - Names and Identifiers
| Name | RBN012759 |
| Synonyms | RBN012759 4(3H)-Quinazolinone, 7-(cyclopropylmethoxy)-5-fluoro-2-[[(trans-4-hydroxycyclohexyl)thio]methyl]- |
| CAS | 2360851-29-0 |
2360851-29-0 - Physico-chemical Properties
| Molecular Formula | C19H23FN2O3S |
| Molar Mass | 378.46 |
| Storage Condition | -20℃ |
| Use | RBN012759, a potent and selective PARP14 inhibitor, decreases pro-tumor macrophage function and elicits inflammatory responses in tumor explants. |
| Target | PARP14 |
2360851-29-0 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.642 ml | 13.211 ml | 26.423 ml |
| 5 mM | 0.528 ml | 2.642 ml | 5.285 ml |
| 10 mM | 0.264 ml | 1.321 ml | 2.642 ml |
| 5 mM | 0.053 ml | 0.264 ml | 0.528 ml |
Last Update：2024-01-02 23:10:35
2360851-29-0 - Reference Information
| biological activity | RBN012759 is an effective and selective PARP14 inhibitor, and its IC50 values for human catalytic domain and mouse catalytic domain are <3 nM and 5 nM respectively. RBN012759 contributes to anti-tumor immune response. |
| target | TargetValue human parp14 (cell-free say) <3 nM mouse parp14 (cell-free say) 5 nM |
| Target | Value |
| human PARP14 (Cell-free assay) | <3 nM |
| mouse PARP14 (Cell-free assay) | 5 nM |
Last Update：2024-04-09 19:05:06
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Product Name: RBN012759 Visit Supplier Webpage Request for quotationCAS: 2360851-29-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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