Name | Acetic acid 5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10(S)-yl ester |
Synonyms | Aptiom APTIOM BIA 2-093 Sep 0002093 Licarbazepine Impurity 4(Licarbazepine Acetate S-Isomer) (S)-5-CarbaMoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl acetate S(+)-10-acetoxy-10,11-Dihydro-10-5H-dibenz[b,f]azepine-5-carboxamide (10S)-10-(Acetyloxy)-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide 5H-Dibenz[b,f]azepine-5-carboxaMide, 10-(acetyloxy)-10,11-dihydro-, (10S)- Acetic acid 5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10(S)-yl ester |
CAS | 236395-14-5 |
EINECS | 636-617-2 |
InChI | InChI=1/C17H16N2O3/c1-11(20)22-16-10-12-6-2-4-8-14(12)19(17(18)21)15-9-5-3-7-13(15)16/h2-9,16H,10H2,1H3,(H2,18,21)/t16-/m0/s1 |
InChIKey | QIALRBLEEWJACW-INIZCTEOSA-N |
Molecular Formula | C17H16N2O3 |
Molar Mass | 296.32 |
Density | 1.32 |
Melting Point | 183-185°C |
Boling Point | 427.4±55.0 °C(Predicted) |
Flash Point | 212.3°C |
Solubility | H2O: insoluble |
Vapor Presure | 1.65E-07mmHg at 25°C |
Appearance | solid |
Color | white |
pKa | 13.97±0.40(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Refractive Index | 1.655 |
In vivo study | Eslicarbazepine acetate(ESL) has antispasmodic effect in latrunculin A- induced epilepsy, spasm, paroxysmal brain electrical activity. In addition to suppressing seizures, it also has the effect of improving the condition, which may be achieved by changing the development of over-excited networks. |
Hazard Symbols | Xi - Irritant![]() |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
WGK Germany | 3 |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 3.375 ml | 16.873 ml | 33.747 ml |
5 mM | 0.675 ml | 3.375 ml | 6.749 ml |
10 mM | 0.337 ml | 1.687 ml | 3.375 ml |
5 mM | 0.067 ml | 0.337 ml | 0.675 ml |