2365-44-8
3-hydrazino-2H-indol-2-one
CAS: 2365-44-8
Molecular Formula: C8H7N3O
2365-44-8 - Names and Identifiers
| Name | 3-hydrazino-2H-indol-2-one |
| Synonyms | Sunitinib Impurity 57 3-hydrazinylindol-2-one 3-Hydrazonoindolin-2-one 3-hydrazino-2H-indol-2-one 3-Hydrazono-1,3-dihydro-2H-indol-2-one |
| CAS | 2365-44-8 |
| InChI | InChI=1/C8H7N3O/c9-11-7-5-3-1-2-4-6(5)10-8(7)12/h1-4H,9H2,(H,10,11,12) |
2365-44-8 - Physico-chemical Properties
| Molecular Formula | C8H7N3O |
| Molar Mass | 161.16 |
| Density | 1.49±0.1 g/cm3(Predicted) |
| Melting Point | 237-238 °C(Solv: ethanol (64-17-5)) |
| Boling Point | 424.8°C at 760 mmHg |
| Flash Point | 210.7°C |
| Vapor Presure | 2.01E-07mmHg at 25°C |
| pKa | 10.63±0.20(Predicted) |
| Storage Condition | 2-8℃ |
| Refractive Index | 1.734 |
2365-44-8 - Risk and Safety
| Hazard Class | IRRITANT |
2365-44-8 - Introduction
It is an organic compound. The following is an introduction to some of its properties, uses, methods and safety information:
Nature:
-chemical formula: C8H7N5O
-Molecular weight: 185.18g/mol
-Appearance: White crystal or crystalline powder
-Melting Point: 187-192 ℃
-Solubility: Slightly soluble in water, easily soluble in organic solvents such as ethanol and chloroform
Use:
-is an important organic synthesis intermediate that can be used to synthesize various organic compounds.
-It can be used to prepare fluorescent dyes, photosensitizers and biomarkers, etc.
Method: The synthesis of
-is obtained by the ammonolysis reaction of carbon dioxide. First, indole -2,3-one reacts with carbamate under basic conditions to produce the corresponding hydrazide intermediate, which is then subjected to oxidation and deprotection reactions to give the product.
Safety Information:
-is not currently classified as a substance that can cause acute or chronic toxicity.
-When handling or using, it is recommended to wear appropriate personal protective equipment, such as chemical goggles and gloves.
-When storing, it should be placed in a dry, dark and well-ventilated place, away from flammable materials and oxidants.
-If inhaled or exposed to the compound, clean the affected area promptly and seek medical help.
Nature:
-chemical formula: C8H7N5O
-Molecular weight: 185.18g/mol
-Appearance: White crystal or crystalline powder
-Melting Point: 187-192 ℃
-Solubility: Slightly soluble in water, easily soluble in organic solvents such as ethanol and chloroform
Use:
-is an important organic synthesis intermediate that can be used to synthesize various organic compounds.
-It can be used to prepare fluorescent dyes, photosensitizers and biomarkers, etc.
Method: The synthesis of
-is obtained by the ammonolysis reaction of carbon dioxide. First, indole -2,3-one reacts with carbamate under basic conditions to produce the corresponding hydrazide intermediate, which is then subjected to oxidation and deprotection reactions to give the product.
Safety Information:
-is not currently classified as a substance that can cause acute or chronic toxicity.
-When handling or using, it is recommended to wear appropriate personal protective equipment, such as chemical goggles and gloves.
-When storing, it should be placed in a dry, dark and well-ventilated place, away from flammable materials and oxidants.
-If inhaled or exposed to the compound, clean the affected area promptly and seek medical help.
Last Update：2024-04-10 22:29:15
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Product Name: Sunitinib Impurity 57 Visit Supplier Webpage Request for quotationCAS: 2365-44-8
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: 3-hydrazinylindol-2-one Visit Supplier Webpage Request for quotation
CAS: 2365-44-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 2365-44-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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