238749-50-3

238749-50-3 - Names and Identifiers

Name	Ethyl2-bromo-4H-thieno[3,2-b]pyrrole-5-carboxylate
Synonyms	Ethyl2-bromo-4H-thieno[3,2-b]pyrrole-5-carboxylate ethyl 2-bromo-4H-thieno[3,2-b]pyrrole-5-carboxylate 2-Bromo-4H-thieno[3,2-b]pyrrole-5-carboxylic acid ethyl ester 4H-Thieno[3,2-b]pyrrole-5-carboxylic acid, 2-bromo-, ethyl e... 4H-Thieno[3,2-b]pyrrole-5-carboxylic acid, 2-bromo-, ethyl ester
CAS	238749-50-3

238749-50-3 - Physico-chemical Properties

Molecular Formula	C9H8BrNO2S
Molar Mass	274.13
Density	1.692±0.06 g/cm3 (20 ºC 760 Torr)
Boling Point	398.8±37.0 °C(Predicted)
Water Solubility	Sparingly soluble in water.
Appearance	Powder
pKa	13.72±0.30(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C

238749-50-3 - Introduction

Ethyl2-bromo-4H-thieno[3,2-b]pyrrole-5-carboxylate is an organic compound with the molecular formula C10H6BrNO2S, The structure contains the ring structure of thiophene and pyrrole, and has a carboxylic acid ethyl ester group.

The properties of the compound are as follows:
-Appearance: Colorless to light yellow crystal
-Melting Point: 82-85 ℃
-Boiling point: 427 ℃
-Solubility: Soluble in ether, chloroform and alcohol solvents, insoluble in water

Ethyl2-bromo-4H-thieno[3,2-b]pyrrole-5-carboxylate have important applications in organic synthesis. They are often used as intermediates or starting materials for the synthesis of other organic compounds, such as drugs, dyes and heterocyclic compounds, etc.

Its preparation method can be obtained through the following steps:
1.2-bromo -4H-thiophene -5-carboxylic acid and ethanol are reacted to generate 2-bromo -4H-thiophene -5-carboxylic acid ethyl ester.
2. Ethyl 2-bromo-4H-thiophene-5-carboxylate is reacted with acetone and base to give ethyl 2-bromo-4H-thieno [3,2-b] pyrrole-5-carboxylate.
3. Ethyl 2-bromo-4H-thieno[3,2-b]pyrrole-5-carboxylate is reacted with base, water and acetic anhydride to give the final product Ethyl2-bromo-4H-thieno[3,2-b]pyrrole-5-carboxylate.

Regarding safety information, it is Ethyl2-bromo-4H-thieno that [3,2-b]pyrrole-5-carboxylate have low toxicity under normal conditions of use. However, as a chemical substance, it is still necessary to follow safe operating procedures. Use should avoid inhalation, skin contact and ingestion. Wear protective gloves, goggles and protective clothing during operation, and ensure that the operation area is well ventilated. In case of accidental contact, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-09 20:45:29