240401-22-3

240401-22-3 - Names and Identifiers

Name	4-Piperidinecarbonitrile,hydrochloride (1:1)
Synonyms	4-Cyanopiperidine Hcl 4-CYANOPIPERIDINE HCL 4-Cyanopiperidine hydrochloride 4-CYANOPIPERIDINE HCL 240401-22-3 Piperidine-4-carbonitrile hydrochloride 4-Piperidinecarbonitrile,monohydrochloride
CAS	240401-22-3

240401-22-3 - Physico-chemical Properties

Molecular Formula	C6H11ClN2
Molar Mass	146.62
Storage Condition	Inert atmosphere,Room Temperature

240401-22-3 - Risk and Safety

UN IDs

UN2811

240401-22-3 - Reference Information

Use

4-cyanopiperidine hydrochloride is used as a research compound.

Preparation

11.9g[75.7mmol] dibutyl formamide (99%) was added to 10g[75.7mmol] 4-piperidinamide (97%) in a suspension of 50ml n-propyl acetate at 20°C for 5 minutes. After 5 minutes, at 20 ℃, 18.91g[158.9mmol] thionyl chloride was added. The addition takes 45 minutes, where the temperature remains constant at 20°C. After the addition, the mixture was stirred for another 18 hours at 20°C. The suspension was filtered and the filter residue was washed with n-propyl acetate. After drying, 8.55g of colorless solids remained. By quantitative NMR spectrum analysis, the 4-cyanopiperidine hydrochloride content is 95% (weight/weight). From this, the yield is calculated as the 73% of the theoretical value.

Last Update：2024-04-09 20:52:54