2417-42-7
N-(3-Acetylphenyl)methanesulfonamide
CAS: 2417-42-7
Molecular Formula: C9H11NO3S
2417-42-7 - Names and Identifiers
| Name | N-(3-Acetylphenyl)methanesulfonamide |
| Synonyms | AURORA 2941 N-(3-Acetylphenyl)methanesulfonamide N-(3-ACETYLPHENYL)METHANESULFONAMIDE Methanesulfonamide, N-(3-acetylphenyl)- |
| CAS | 2417-42-7 |
2417-42-7 - Physico-chemical Properties
| Molecular Formula | C9H11NO3S |
| Molar Mass | 213.25 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD00664903 |
2417-42-7 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
2417-42-7 - Introduction
N-(3-Acetylphenyl)methanesulfonamide is an organic compound with the chemical formula C10H11NO3S. The following is an introduction to some of its properties, uses, methods and safety information:
Nature:
-Appearance: N-(3-Acetylphenyl)methanesulfonamide is a white crystalline solid.
-Solubility: It can be dissolved in some organic solvents, such as ethanol, ether and ketone, but it is less soluble in water.
-It is a stable compound that will not decompose or deteriorate under normal storage conditions.
Use:
N-(3-Acetylphenyl)methanesulfonamide has certain applications in the field of pharmaceutical synthesis and organic synthesis:
-In drug synthesis, it can be used as an intermediate to synthesize a variety of pharmaceutically active molecules, such as anti-cancer drugs, anti-inflammatory drugs, etc.
-In organic synthesis, it can be used as a raw material for sulfonamide compounds to participate in various organic reactions, such as coupling reactions, acylation reactions, etc.
Preparation Method:
The preparation of N-(3-Acetylphenyl)methanesulfonamide is generally carried out by the following steps:
1. Benzylamine reacts with acetyl chloride to generate N-acetyl benzylamine.
2. N-Acetyl benzylamine is reacted with methanesulfonyl chloride to generate N-(3-Acetylphenyl)methanesulfonamide. The preparation may require the use of organic solvents and catalysts.
Safety Information:
N-(3-Acetylphenyl)methanesulfonamide has limited understanding of safety and is required to comply with general chemical laboratory practices when used:
-It may be irritating to the eyes, skin and respiratory system. Take appropriate protective measures when exposed, such as gloves, goggles and chemical protective clothing.
-It should be stored in a dry, well-ventilated place, away from fire and oxidizing agents.
-Before use, you should carefully read and follow the relevant safety data form to understand more detailed safety operation information.
Nature:
-Appearance: N-(3-Acetylphenyl)methanesulfonamide is a white crystalline solid.
-Solubility: It can be dissolved in some organic solvents, such as ethanol, ether and ketone, but it is less soluble in water.
-It is a stable compound that will not decompose or deteriorate under normal storage conditions.
Use:
N-(3-Acetylphenyl)methanesulfonamide has certain applications in the field of pharmaceutical synthesis and organic synthesis:
-In drug synthesis, it can be used as an intermediate to synthesize a variety of pharmaceutically active molecules, such as anti-cancer drugs, anti-inflammatory drugs, etc.
-In organic synthesis, it can be used as a raw material for sulfonamide compounds to participate in various organic reactions, such as coupling reactions, acylation reactions, etc.
Preparation Method:
The preparation of N-(3-Acetylphenyl)methanesulfonamide is generally carried out by the following steps:
1. Benzylamine reacts with acetyl chloride to generate N-acetyl benzylamine.
2. N-Acetyl benzylamine is reacted with methanesulfonyl chloride to generate N-(3-Acetylphenyl)methanesulfonamide. The preparation may require the use of organic solvents and catalysts.
Safety Information:
N-(3-Acetylphenyl)methanesulfonamide has limited understanding of safety and is required to comply with general chemical laboratory practices when used:
-It may be irritating to the eyes, skin and respiratory system. Take appropriate protective measures when exposed, such as gloves, goggles and chemical protective clothing.
-It should be stored in a dry, well-ventilated place, away from fire and oxidizing agents.
-Before use, you should carefully read and follow the relevant safety data form to understand more detailed safety operation information.
Last Update：2024-04-09 15:18:11
