Name | Hydroxyphenylhydantoin |
Synonyms | RARECHEM AP KH 0026 Hydroxyphenylhydantoin P-Hydroxyphenylhydantoin 4-HYDROXYPHENYL HYDANTOIN 4-Hydroxyphenyl Hydantoin 5-(4-Hydroxyphenyl)hydantoin 5-(4-HYDROXYPHENYL)HYDANTOIN 5-(P-HYDROXYPHENYL)HYDANTOIN 5-(4-Hydroxylphenyl)hydantoin DL-Para-Hydroxyphenyl Hydantoin 5-(4-Hydroxyphenyl)2,4-Imidazolidinedine 5-(4-HYDROXYPHENYL)2,4-IMIDAZOLIDINEDIONE 5-(4-hydroxyphenyl)imidazolidine-2,4-dione |
CAS | 2420-17-9 54832-24-5 |
EINECS | 219-340-8 |
InChI | InChI=1/C9H8N2O3/c12-6-3-1-5(2-4-6)7-8(13)11-9(14)10-7/h1-4,7,12H,(H2,10,11,13,14) |
Molecular Formula | C9H8N2O3 |
Molar Mass | 192.17 |
Density | 1.408 |
Melting Point | >260°C |
Boling Point | 273.7℃[at 101 325 Pa] |
Water Solubility | 1.29g/L at 20℃ |
Vapor Presure | 0Pa at 25℃ |
Appearance | powder to crystal |
Color | White to Almost white |
pKa | 8.67±0.10(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
Refractive Index | 1.607 |
MDL | MFCD00044002 |
Hazard Symbols | Xn - Harmful |
Risk Codes | R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. |
LogP | -0.03 at 20℃ |
Use | Used to synthesize p-hydroxyphenylglycine, thereby further preparing semi-synthetic penicillin and cephalosporin It is used to produce amoxicillin, Cephalosporin and other D-p-hydroxyphenylglycine is an important pharmaceutical intermediate, is the side chain of the synthesis of β-lactam semi-synthetic antibiotics, used to produce amoxicillin, and other antibiotic drugs, it has the characteristics of broad-spectrum antibacterial and convenient medication. |