243990-54-7

243990-54-7 - Names and Identifiers

Name	3-(Benzyloxy)-4-methoxyphenylboronic acid
Synonyms	3-(Benzyloxy)-4-methoxyphenylboronic acid Boronic acid, B-[4-methoxy-3-(phenylmethoxy)phenyl]-
CAS	243990-54-7

243990-54-7 - Physico-chemical Properties

Molecular Formula	C14H15BO4
Molar Mass	258.0775
Density	1.21±0.1 g/cm3(Predicted)
Boling Point	444.3±55.0 °C(Predicted)
pKa	8.48±0.10(Predicted)
Storage Condition	Inert atmosphere,2-8°C

243990-54-7 - Upstream Downstream Industry

Raw Materials

2-(Benzyloxy)-4-bromo-1-methoxybenzene
5-Bromo-2-methoxyphenol
5-Bromo-2-methoxyphenylacetate
2-METHOXYPHENYL ACETATE
Guaiacol
Benzyl bromide
Trimethyl borate

243990-54-7 - Introduction

3-(Benzyloxy)-4-methoxybenzeneboronic acid is an Organoboron compound with the chemical formula C14H15BO4. It has the form of a white solid.

Nature:
-Appearance: White solid
-Melting Point: about 210-215 ° C
-Solubility: Soluble in acetonitrile and dichloromethane

Use:
-As an important reagent in organic synthesis, it participates in Suzuki-Miyaura reactions, Heck reactions and other reactions, and is used to construct carbon-carbon bonds.
-In drug synthesis, it is often used to introduce benzyloxy and methoxy functional groups.

Method:
3-(Benzyloxy)-4-methoxybenzeneboronic acid can be prepared by the following steps:
1. With 4-methoxyphenylboronic acid as starting material, it reacts with phenylacetylene to obtain 3-(benzyloxy)-4-methoxyphenylboronic acid.
2. Subsequently, the target product 3-(benzyloxy)-4-methoxybenzeneboronic acid was synthesized under the action of hydrochloric acid.

Safety Information:
Safety information on 3-(benzyloxy)-4-methoxybenzeneboronic acid has not been reported in detail. When using and handling, should follow the safe use of regular chemical reagents, such as wearing personal protective equipment (such as gloves, glasses, etc.), avoid direct contact with the compound.

Note: The risk of this compound should be controlled by implementing laboratory air exhaust and careful cleaning of the wiping area and other control measures when the equipment and experimental conditions permit. It is strongly recommended to carefully read and comply with the safety data sheet (SDS) provided with this compound before using it.

Last Update：2024-04-09 21:54:55