Molecular Formula | C15H23N3O4 |
Molar Mass | 309.36 |
Density | 1.208±0.06 g/cm3(Predicted) |
Melting Point | 153.5 °C |
Boling Point | 460.6±45.0 °C(Predicted) |
pKa | 15.86±0.50(Predicted) |
Storage Condition | 2-8°C,密封,干燥 |
biological activity | Gefitinib importance 2 is an impurity of Gefitinib. Gefitinib (HY-50895) is a potent, orally active selective EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 54 nM) and blocks EGFR autophosphorylation in EGF-stimulated tumor cells. Gefitinib can also induce autophagy in cells. Gefitinib has anti-tumor activity. |