24730-31-2
surfactin
CAS: 24730-31-2
Molecular Formula: C53H93N7O13
24730-31-2 - Names and Identifiers
24730-31-2 - Physico-chemical Properties
| Molecular Formula | C53H93N7O13 |
| Molar Mass | 1036.34462 |
| Density | 1.037±0.06 g/cm3(Predicted) |
| Melting Point | 140-144°C |
| Boling Point | 1268.3±65.0 °C(Predicted) |
| Appearance | Shape powder, color white to fail yellow |
| pKa | 4.00±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Stability | Stable, but store below 10 C. Incompatible with strong oxidizing agents. |
| Physical and Chemical Properties | Bioactive Surfactin is a cyclic lipopeptide biosurfactant that mediates the flux of monovalent and divalent cations such as calcium ions across the lipid bilayer membrane. Surfactin can be used as an antimicrobial adjuvant with antibacterial, antifungal, antimycoplasma and hemolytic effects. Surfactin also has antiviral activity against a variety of enveloped viruses. |
24730-31-2 - Risk and Safety
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10 |
24730-31-2 - Uses and synthesis methods
Target
HSV-1
HSV-2
in vitro studies
Surfactin can increase the activity of NSC277174 against avian pathogenic Escherichia coli (APEC) in vitro with antimicrobial assays such as minimum inhibitory concentrations (MIC) and fractional inhibitory concentration (FIC). For APEC O78 strain, the MIC of NSC277174 and Surfactin are 1000 ug/ml and >1mg/ml, respectively.
In vivo studies
In the model of chick infection (inoculation of E.coli ), Surfactin exerts adjuvant effects with NSC277174 against APEC by lowering the numerical value of mortality and liver bacterial loads, and regulating the expression of inflammatory cytokines et al. Surfactin can act as a novel antimicrobial adjuvant with NSC277174 against AEPC infection in chicken.
Last Update：2024-04-09 18:58:34
24730-31-2 - Nature
| Solubility | ethanol: 10 mg/mL, clear, slightly yellow |
Last Update：2024-04-09 19:04:56
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