247564-73-4
2,3,5-Trifluorophenylboronic acid
CAS: 247564-73-4
Molecular Formula: C6H4BF3O2
247564-73-4 - Names and Identifiers
247564-73-4 - Physico-chemical Properties
| Molecular Formula | C6H4BF3O2 |
| Molar Mass | 175.9 |
| Density | 1.44±0.1 g/cm3(Predicted) |
| Melting Point | 221 °C (dec.) (lit.) |
| Boling Point | 269.3±50.0 °C(Predicted) |
| Solubility | soluble in Methanol |
| Appearance | powder to crystal |
| Color | White to Almost white |
| pKa | 6.26±0.58(Predicted) |
| Storage Condition | 2-8°C |
247564-73-4 - Risk and Safety
| WGK Germany | 3 |
247564-73-4 - Introduction
2,3,5-Trifluorophenylboronic acid is an organic compound with the chemical formula C6H4BF3O2. It is a solid crystal with a white or light yellow color. The following is a brief description of the nature, use, preparation and safety information of 2,3,5-Trifluorophenylboronic acid:
Nature:
-Appearance: White or light yellow solid crystal
-Density: approx. 1.44g/cm³
-Melting point: About 156-159 ° C
-Solubility: Soluble in some organic solvents, such as chloroform, dichloromethane
Use:
- 2,3,5-Trifluorophenylboronic acid is an important reagent in organic synthesis and can be used as a catalyst and substrate for Suzuki reaction.
-It can also be used to prepare other organic compounds, such as fluorescent dyes, biomarkers, pharmaceutical intermediates, etc.
-In drug research, 2,3,5-Trifluorophenylboronic acid is also widely used.
Method:
The preparation of 2,3,5-Trifluorophenylboronic acid is usually achieved by a response reaction. The commonly used methods include the substitution reaction of trifluorophenylboronic acid and Phenylboronic acid. Specific steps can refer to organic synthetic chemistry literature.
Safety Information:
2,3,5-Trifluorophenylboronic acid is generally believed to have no obvious acute toxic effect on human body under general operating conditions. However, as an organic compound, it is still necessary to pay attention to the following matters:
-Avoid prolonged exposure to the substance to avoid inhalation or contact with the skin.
-Good ventilation during operation and use of personal protective equipment such as gloves, goggles, etc.
-Wash the affected area immediately and seek medical help, such as accidental contact or inhalation.
Nature:
-Appearance: White or light yellow solid crystal
-Density: approx. 1.44g/cm³
-Melting point: About 156-159 ° C
-Solubility: Soluble in some organic solvents, such as chloroform, dichloromethane
Use:
- 2,3,5-Trifluorophenylboronic acid is an important reagent in organic synthesis and can be used as a catalyst and substrate for Suzuki reaction.
-It can also be used to prepare other organic compounds, such as fluorescent dyes, biomarkers, pharmaceutical intermediates, etc.
-In drug research, 2,3,5-Trifluorophenylboronic acid is also widely used.
Method:
The preparation of 2,3,5-Trifluorophenylboronic acid is usually achieved by a response reaction. The commonly used methods include the substitution reaction of trifluorophenylboronic acid and Phenylboronic acid. Specific steps can refer to organic synthetic chemistry literature.
Safety Information:
2,3,5-Trifluorophenylboronic acid is generally believed to have no obvious acute toxic effect on human body under general operating conditions. However, as an organic compound, it is still necessary to pay attention to the following matters:
-Avoid prolonged exposure to the substance to avoid inhalation or contact with the skin.
-Good ventilation during operation and use of personal protective equipment such as gloves, goggles, etc.
-Wash the affected area immediately and seek medical help, such as accidental contact or inhalation.
Last Update：2024-04-09 15:17:56
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