25365-71-3

25365-71-3 - Names and Identifiers

Name	2-Phenylindole-3-carboxaldehyde
Synonyms	AURORA 23280 AKOS SVR00140 ART-CHEM-BB B023284 OTAVA-BB BB7214110035 3-FORMYL-2-PHENYL-INDOLE 2-PHENYLINDOLE-3-ALDEHYDE 2-PHENYLINDOLE-3-CARBOXALDEHYDE 2-Phenylindole-3-carboxaldehyde 2-phenyl-1H-indole-3-carbaldehyde 2-PHENYL-1H-INDOLE-3-CARBALDEHYDE 1h-indole-3-carboxaldehyde, 2-phenyl-
CAS	25365-71-3
InChI	InChI=1/C15H11NO/c17-10-13-12-8-4-5-9-14(12)16-15(13)11-6-2-1-3-7-11/h1-10,16H

25365-71-3 - Physico-chemical Properties

Molecular Formula	C15H11NO
Molar Mass	221.25
Density	1.237±0.06 g/cm3(Predicted)
Melting Point	249-253 °C (lit.)
Boling Point	462.9±33.0 °C(Predicted)
Flash Point	237.5°C
Vapor Presure	9.47E-09mmHg at 25°C
pKa	15.30±0.30(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Sensitive	Air Sensitive
Refractive Index	1.709
MDL	MFCD00435481

25365-71-3 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3
HS Code	29339900
Hazard Class	IRRITANT

25365-71-3 - Introduction

It is a compound commonly used in organic synthesis. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: Colorless to light yellow crystal
-molecular formula: C15H11NO
-Molecular weight: 221.25g/mol
-Melting Point: 82-84 ℃
-Boiling point: 390 ℃ (expected)

Use:
It has a variety of uses in chemical experiments, including:
-As an intermediate in Organic Synthesis: It can be used to synthesize compounds with indole structure, such as indole derivatives and malachite green.
-As a fluorescent dye: It can be used as a fluorescent probe in cell and molecular microscopy to detect DNA, RNA and proteins.

Method:
The preparation method can be carried out by the following steps:
1. Indole and benzonitrile are reacted by heating in a suitable reaction solvent. The reaction is usually carried out within 1 to 5 hours.
2. Add an appropriate oxidizing agent, such as cuprous chloride or hydrogen peroxide, and continue the reaction.
3. The crude product is obtained by filtration and purified by appropriate purification methods (such as crystallization, washing, distillation).

Safety Information:
-may cause irritation to the eyes, skin, and respiratory system, so wear appropriate personal protective equipment, such as glasses, gloves, and face mask.
-Avoid inhalation, ingestion or contact with skin. Operate in a well-ventilated area or wear respiratory protective equipment.
-Be careful when handling the compound and avoid direct contact. Handle and store according to laboratory procedures.
-should be stored in a cool, dry, airtight container, away from fire and oxidizing agents.

Last Update：2024-04-10 22:29:15