25391-58-6

25391-58-6 - Names and Identifiers

Name	3-iodo-5-nitropyridin-2(1H)-one
Synonyms	3-Iodo-5-nitropyridin-2-ol 3-IODO-5-NITROPYRIDIN-2-OL 3-iodo-5-nitropyridin-2(1H)-one 2(1H)-Pyridinone, 3-iodo-5-nitro- 2-HYDROXY-3-IODO-5-NITROPYRIDINE 97 3-iodo-5-nitro-1,2-dihydropyridin-2-one
CAS	25391-58-6
InChI	InChI=1/C5H3IN2O3/c6-4-1-3(8(10)11)2-7-5(4)9/h1-2H,(H,7,9)

25391-58-6 - Physico-chemical Properties

Molecular Formula	C5H3IN2O3
Molar Mass	265.99
Density	2.27±0.1 g/cm3(Predicted)
Melting Point	203-207°C(lit.)
Boling Point	317.9±42.0 °C(Predicted)
Flash Point	146.062°C
Vapor Presure	0mmHg at 25°C
pKa	6.62±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Refractive Index	1.703

25391-58-6 - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R22 - Harmful if swallowed R41 - Risk of serious damage to eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection.
WGK Germany	3

25391-58-6 - Introduction

3-iodo-5-nitropyridin-2(1H)-one is an organic compound with the chemical formula C5H3IN2O3.

Nature:
The compound is a white solid with a high melting point and boiling point. It is insoluble in water, but soluble in organic solvents such as ethanol and acetone.

Use:
3-iodo-5-nitropyridin-2(1H)-one has a variety of applications, including as an intermediate and reagent in organic synthesis:
-Used to prepare other compounds, such as drugs, dyes and photoelectric materials.
-In organic synthesis, it can be used as a reagent for para-substitution reactions, such as reacting with Grignard reagents to form substituted hydroxyl groups.

Method:
Generally, 3-iodo-5-nitropyridin-2(1H)-one is prepared by para-substitution reaction on the pyridine ring. There may be a variety of options for specific synthetic methods, such as one of the following synthetic routes:
2-chloro-5-nitropyridine and iodic acid are converted to 3-iodo-5-nitropyridin-2(1H)-one by reaction.

Safety Information:
3-iodo-5-nitropyridin-2(1H)-one is relatively safe under general conditions of use. However, as an organic compound, the following safety measures should be taken:
-Avoid contact with skin and eyes to avoid irritation and allergic reactions.
-Use appropriate protective gloves, safety glasses and protective clothing during operation.
-Follow proper operating procedures and laboratory safety regulations.
-Follow local regulations and safety guidelines when storing and handling.

Please note that this is only general information. Specific experimental operations and safety measures may vary according to specific circumstances and should be carried out under the guidance of professionals.

Last Update：2024-04-09 20:45:29