2629-55-2

2629-55-2 - Names and Identifiers

Name	3-(2-Fluorophenyl)-DL-alanine
Synonyms	h-dl-phe(2-f)-oh H-DL-Phe(2-F)-OH 2-FLUORO-DL-PHENYLAL 2-fluoro-phenylalanin 2-Fluoro-DL-phenylalanine DL-3-(2-Fluorophenyl)alanine 3-(2-Fluorophenyl)-DL-alanine o-FLUORO-DL-PHENYLALANINE extrapure DL-2-F-Phe-OH 2-Fluoro-DL-Phenylalanine DL-2-Amino-3-(2-fluoro-phenyl)-propionic acid
CAS	2629-55-2
EINECS	220-105-7
InChI	InChI=1/C9H10FNO2/c10-7-4-2-1-3-6(7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)
InChIKey	NYCRCTMDYITATC-UHFFFAOYSA-N

2629-55-2 - Physico-chemical Properties

Molecular Formula	C9H10FNO2
Molar Mass	183.18
Density	1.1939 (estimate)
Melting Point	243-246°C(lit.)
Boling Point	308.1±32.0 °C(Predicted)
BRN	3201186
pKa	pK1:2.14(＋1);pK2:9.01(0) (25°C)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
MDL	MFCD00004271

2629-55-2 - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	24/25 - Avoid contact with skin and eyes.
UN IDs	2811
WGK Germany	3
RTECS	AY6307000
Hazard Note	Harmful
Hazard Class	6.1
Packing Group	III

2629-55-2 - Introduction

3-(2-Fluorophenyl)-DL-alanine is an organic compound with the chemical formula C9H10FNO2. The following is a detailed description of the properties, uses, preparation methods and safety information of the compound:

Nature:
3-(2-Fluorophenyl)-DL-alanine is a colorless crystalline solid with a slightly sweet taste at room temperature. It is soluble in water and some organic solvents such as ethanol and dichloromethane. It is a compound with stereoisomers, including both the D-isomer and the L-isomer.

Use:
3-(2-Fluorophenyl)-DL-alanine has certain applications in the pharmaceutical industry. It is an unnatural amino acid that can act as a catalyst in the synthesis of organic compounds as a chiral reagent. In addition, it is also used as an intermediate in the synthesis of biologically active compounds, such as synthetic drugs and pesticides.

Method:
The synthesis of 3-(2-Fluorophenyl)-DL-alanine is mainly divided into two steps. First, a fluorine atom is introduced into the α-hydroxyl group of alanine, usually using a nucleophilic substitution reaction like benzylammonium bromide. Then, the introduced fluorine atom is reduced to hydrogen by a reduction reaction to obtain a target product.

Safety Information:
3-(2-Fluorophenyl)-DL-alanine has low toxicity, but it is still necessary to pay attention to safe use. As with most chemicals, use should follow laboratory procedures. Avoid direct contact with skin and eyes to avoid irritation or injury. Keep away from fire and heat sources during use and storage, and avoid contact with oxidants.

Last Update：2024-04-09 21:01:54