267880-92-2
3-(4-Bromo-2-fluorophenyl)-3-oxopropanenitrile
CAS: 267880-92-2
Molecular Formula: C9H5BrFNO
267880-92-2 - Names and Identifiers
267880-92-2 - Physico-chemical Properties
| Molecular Formula | C9H5BrFNO |
| Molar Mass | 242.04 |
| Melting Point | 116-118 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD09607907 |
267880-92-2 - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
267880-92-2 - Introduction
3-(4-Bromo-2-fluorophenyl)-3-oxopropanenitril is an organic compound with the chemical formula C9H4BrFNO. It is a solid with a white to pale yellow color. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White to light yellow solid
-melting point: about 150-155 ℃
-Molecular weight: 241.04g/mol
-Solubility: Soluble in some organic solvents, such as chloroform and dimethyl sulfoxide
Use:
- 3-(4-Bromo-2-fluorophenyl)-3-oxopropanenitril can be used as an intermediate and raw material for chemical synthesis, and can be used to synthesize various organic compounds.
-It is also used in the field of drug research and can be used as a precursor of certain drugs.
Preparation Method:
- 3-(4-Bromo-2-fluorophenyl)-3-oxopropanenitrile can be synthesized by different methods. The following is a possible synthesis method:
1. First, sodium cyanide was gradually added to the acetonitrile solution of 4-bromo-2-fluorophenyl sodium cyanide in an ice-water bath.
2. Ethyl acetate was then added and the reaction stirred at room temperature for several hours.
3. Finally, the solid in the reaction mixture is separated by filtration and washed with an appropriate organic solvent.
Safety Information:
- 3-(4-Bromo-2-fluorophenyl)-3-oxopropanenitril is an organic compound and should be handled with care.
-Wear appropriate protective equipment such as lab gloves and goggles during use.
-It may cause harm to the environment, should avoid a large number of leakage into the soil and water.
-During storage and handling, please refer to the relevant safety data sheets and operating instructions to ensure your own safety and protect the environment.
Nature:
-Appearance: White to light yellow solid
-melting point: about 150-155 ℃
-Molecular weight: 241.04g/mol
-Solubility: Soluble in some organic solvents, such as chloroform and dimethyl sulfoxide
Use:
- 3-(4-Bromo-2-fluorophenyl)-3-oxopropanenitril can be used as an intermediate and raw material for chemical synthesis, and can be used to synthesize various organic compounds.
-It is also used in the field of drug research and can be used as a precursor of certain drugs.
Preparation Method:
- 3-(4-Bromo-2-fluorophenyl)-3-oxopropanenitrile can be synthesized by different methods. The following is a possible synthesis method:
1. First, sodium cyanide was gradually added to the acetonitrile solution of 4-bromo-2-fluorophenyl sodium cyanide in an ice-water bath.
2. Ethyl acetate was then added and the reaction stirred at room temperature for several hours.
3. Finally, the solid in the reaction mixture is separated by filtration and washed with an appropriate organic solvent.
Safety Information:
- 3-(4-Bromo-2-fluorophenyl)-3-oxopropanenitril is an organic compound and should be handled with care.
-Wear appropriate protective equipment such as lab gloves and goggles during use.
-It may cause harm to the environment, should avoid a large number of leakage into the soil and water.
-During storage and handling, please refer to the relevant safety data sheets and operating instructions to ensure your own safety and protect the environment.
Last Update：2024-04-09 21:01:54
