26830-96-6
2-amino-4-methylbenzonitrile
CAS: 26830-96-6
Molecular Formula: C8H8N2
26830-96-6 - Names and Identifiers
| Name | 2-amino-4-methylbenzonitrile |
| Synonyms | 2-Cyano-5-methylaniline 2-AMINO-4-METHYLBENZONITRILE 4-Methyl-2-aminobenzonitrile 2-amino-4-methylbenzonitrile Benzonitrile, 2-aMino-4-Methyl- 2-Cyano-5-methylaniline, 3-Amino-4-cyanotoluene 3-Amino-4-cyanotoluene2-Cyano-5-methylaniline6-Cyano-m-toluidine 2-Cyano-5-methylaniline, 3-Amino-4-cyanotoluene, 6-Cyano-m-toluidine |
| CAS | 26830-96-6 |
| EINECS | 248-020-0 |
| InChI | InChI=1/C8H8N2/c1-6-2-3-7(5-9)8(10)4-6/h2-4H,10H2,1H3 |
26830-96-6 - Physico-chemical Properties
| Molecular Formula | C8H8N2 |
| Molar Mass | 132.16 |
| Density | 1.10±0.1 g/cm3(Predicted) |
| Melting Point | 92-95 °C (lit.) |
| Boling Point | 150-152 °C(Press: 15 Torr) |
| Flash Point | 135.964°C |
| Solubility | soluble in Methanol |
| Vapor Presure | 0.001mmHg at 25°C |
| Appearance | Powder |
| Color | Light yellow to Yellow to Orange |
| pKa | 1.94±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.576 |
26830-96-6 - Risk and Safety
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S36/37 - Wear suitable protective clothing and gloves. |
| UN IDs | 3439 |
| WGK Germany | 3 |
| HS Code | 29269090 |
| Hazard Note | Toxic |
| Hazard Class | 6.1 |
| Packing Group | III |
26830-96-6 - Introduction
It is a chemical with the chemical formula C9H9N. The following is a description of its nature, use, formulation and safety information:
Nature:
is a white solid with a structure of benzene ring and nitrile group. It is insoluble in water at normal temperature, but soluble in many organic solvents such as ethanol and ether.
Use:
It is often used as a chemical synthesis intermediate. It has a variety of synthetic methods and can be applied to the synthesis of drugs in the field of biomedicine, such as the synthesis of anti-cancer drugs, antiviral drugs and so on.
Method:
A commonly used method of preparation is to obtain the corresponding nitrile compound by reacting p-tolualdehyde and hydrocyanic acid, and then treating the phosphonium with ammonia under alkaline conditions.
Safety Information:
There is no clear literature on specific safety information, but in general, necessary safety measures should be taken when handling chemical substances. It may have an irritating effect on the eyes, skin and respiratory tract, so direct contact should be avoided. Wear appropriate protective equipment such as gloves, glasses and suitable protective clothing during operation. Store at low temperature and keep away from fire and oxidant. During use, attention should be paid to well-ventilated laboratory conditions to prevent the accumulation of harmful gases. Disposal of waste should be done in accordance with local regulations.
Please note that the information provided above is for reference only, and the specific safety operation should be evaluated and determined according to the actual situation and relevant literature.
Nature:
is a white solid with a structure of benzene ring and nitrile group. It is insoluble in water at normal temperature, but soluble in many organic solvents such as ethanol and ether.
Use:
It is often used as a chemical synthesis intermediate. It has a variety of synthetic methods and can be applied to the synthesis of drugs in the field of biomedicine, such as the synthesis of anti-cancer drugs, antiviral drugs and so on.
Method:
A commonly used method of preparation is to obtain the corresponding nitrile compound by reacting p-tolualdehyde and hydrocyanic acid, and then treating the phosphonium with ammonia under alkaline conditions.
Safety Information:
There is no clear literature on specific safety information, but in general, necessary safety measures should be taken when handling chemical substances. It may have an irritating effect on the eyes, skin and respiratory tract, so direct contact should be avoided. Wear appropriate protective equipment such as gloves, glasses and suitable protective clothing during operation. Store at low temperature and keep away from fire and oxidant. During use, attention should be paid to well-ventilated laboratory conditions to prevent the accumulation of harmful gases. Disposal of waste should be done in accordance with local regulations.
Please note that the information provided above is for reference only, and the specific safety operation should be evaluated and determined according to the actual situation and relevant literature.
Last Update：2024-04-09 21:54:55
