2687-44-7

2687-44-7 - Names and Identifiers

2687-44-7 - Physico-chemical Properties

Molecular Formula	C5H9NO
Molar Mass	99.13
Density	1.028 g/mL at 25 °C (lit.)
Melting Point	-24 °C (lit.)
Boling Point	202 °C (lit.)81-82 °C/10 mmHg (lit.)
Flash Point	187°F
Water Solubility	>=10 g/100 mL at 20 ºC
Solubility	ethanol: miscible0.1ML/mL, clear, colorless (10%, v/v)
Vapor Presure	0.29 mm Hg ( 20 °C)
Vapor Density	3.4 (vs air)
Appearance	Liquid
Color	≤20(APHA)
Odor	Slight amine odor
Maximum wavelength(λmax)	['283nm(MeOH)(lit.)']
Merck	14,6117
BRN	106420
pKa	-0.41±0.20(Predicted)
PH	8.5-10.0 (100g/l, H2O, 20℃)
Storage Condition	Store at +5°C to +30°C.
Stability	Stable, but decomposes upon exposure to light. Combustible. Incompatible with strong oxidizing agents, strong acids, reducing agents, bases.
Sensitive	Hygroscopic
Explosive Limit	1.3-9.5%(V)
Refractive Index	n20/D 1.479
Physical and Chemical Properties	Characteristics of colorless transparent oily liquid, slightly amine odor. melting point -24.4 ℃ boiling point 203 ℃ relative density 1.0260 refractive index 1.486 flash point 95 ℃ , ether, Ester, ketone, halogenated hydrocarbon, aromatic hydrocarbon miscible.
Use	Widely used in advanced lubricating oil refining, polymer synthesis, insulating materials, pesticides, pigments and cleaning agents

2687-44-7 - Risk and Safety

Risk Codes	R45 - May cause cancer R65 - Harmful: May cause lung damage if swallowed R36/38 - Irritating to eyes and skin. R36/37/38 - Irritating to eyes, respiratory system and skin. R61 - May cause harm to the unborn child R10 - Flammable R46 - May cause heritable genetic damage
Safety Description	S41 - In case of fire and / or explosion do not breathe fumes. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S53 - Avoid exposure - obtain special instructions before use. S62 - If swallowed, do not induce vomitting; seek medical advice immediately and show this container or label. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany	1
RTECS	UY5790000
FLUKA BRAND F CODES	3-8-10
TSCA	Y
HS Code	2933199090
Toxicity	LD50 orally in Rabbit: 3598 mg/kg LD50 dermal Rabbit 8000 mg/kg

2687-44-7 - Upstream Downstream Industry

Raw Materials

gamma-butyrolactone
Methylamine
Methylamine

2687-44-7 - Nature

Open Data Verified Data

colorless transparent oily liquid. It is miscible with water, alcohol, ether, Ester, ketone, halogenated hydrocarbon and aromatic hydrocarbon.

Last Update：2024-01-02 23:10:35

2687-44-7 - Quality Standard

Open Data Verified Data

purity 95%; Moisture less than 1.3%; Refractive index greater than 4655.

Last Update：2022-01-01 09:24:30

2687-44-7 - Preparation Method

Open Data Verified Data

& gamma;-butyrolactone is reacted with methylamine. After completion of the reaction, the reaction is cooled, Excess methylamine and water are removed, and the product is concentrated, followed by distillation under reduced pressure.

Last Update：2022-01-01 09:24:31

2687-44-7 - Use

Open Data Verified Data

excellent advanced solvent, widely used in petrochemical, pesticide, medical, electronic materials and other fields. It can be used for synthesis gas desulfurization, lubricating oil refining, lubricating oil antifreeze, olefin extractant, agricultural herbicide, insulating material, integrated circuit production, pvc tail gas recovery, cleaning agent, Dye auxiliary agent, dispersant, etc.

Last Update：2022-01-01 09:24:32

2687-44-7 - Safety

Open Data Verified Data

mouse, rat LD50( mL/kg):3.5, 2.2 (intravenous);4.3, 3. 4 (intraperitoneal injection);7.5, 3. 8 (by mouth). The allowable limit concentration in air is 100 x lO-6. Flammable liquid should be sealed and protected from moisture and light.

Last Update：2022-01-01 09:24:32

2687-44-7 - Reference Information

pH range of acid-base indicator discoloration	7.7 - 8.0
LogP	-0.46 at 25℃
NIST chemical information	information provided by: webbook.nist.gov (external link)
EPA chemical substance information	information provided by: ofmpeb.epa.gov (external link)
Overview	N-methylpyrrolidone (NMP), molecular formula: C5H9NO, English: 1-methyl-2-pyrrollidinone, appearance is colorless to light yellow transparent liquid, slightly ammonia odor, miscible with water in any proportion, soluble in ether, acetone and Ester, halogenated hydrocarbons, aromatic hydrocarbons and other organic solvents, almost completely mixed with all solvents, boiling point 204 ℃, flash point 91 ℃, strong hygroscopicity, stable chemical properties, no corrosion to carbon steel, aluminum, slightly corrosive to copper. It has the advantages of low viscosity, good chemical stability and thermal stability, high polarity, low volatility, infinite miscibility with water and many organic solvents. This product is a micro drug, the allowable limit concentration in the air is 100PPM.
reference quality index	inspection item index appearance colorless transparent liquid (above 25 ℃) purity% ≥ 99.5 moisture% ≤ 0.1 chroma HaZen ≤ 25 refractive index N20D 1.468-1.471 density 1.032-1.035
Use	N-methylpyrrolidone (NMP) is a polar aprotic solvent. With low toxicity, high boiling point, superior dissolution. The advantages of strong selectivity and good stability. Widely used in aromatic extraction, acetylene, olefin, Diene purification, polyvinylidene fluoride solvent, lithium ion battery electrode auxiliary material, synthesis gas desulfurization, lubricating oil refining, lubricating oil antifreeze, olefin extraction agent, insoluble engineering plastics polymerization solvents, agricultural herbicides, insulating materials, integrated circuit manufacturing, semiconductor industry precision instruments, circuit board cleaning, PVC tail gas recovery, cleaning agents, dye additives, dispersants, etc. It is also used as a solvent for polymers and as a medium for polymerization, such as engineering plastics and aramid fibers. In addition, it can also be used in pesticides, pharmaceuticals, detergents and the like. The main uses of different grades of N-methyl pyrrolidone are listed below: 1. Industrial grade: lubricating oil refining, lubricating oil antifreeze, synthesis gas desulfurization, electronic insulation materials, agricultural herbicides, pesticide additives, PVC tail gas recovery, high-grade coatings, inks, pigments and other production additives and dispersants. For example, it can be used as a solvent for extracting aromatic hydrocarbons in lubricating oil to achieve the purpose of refining lubricating oil. Because NMP has great solubility to resin, it can be used as a solvent for resin processing in the manufacture of coatings, floor paints, varnishes, composite coating film, integrated circuit enameled wire insulation materials, fiber fabrics and adhesives and other products. 2. Ordinary Grade: Extraction and recovery of basic organic raw materials, such as acetylene concentration and extraction of butadiene, isoprene and aromatic hydrocarbons. It can be used as a solvent for recovering acetylene from natural gas or light naphtha thermal pyrolysis gas, and the purity of the Concentrated Acetylene can be recovered to 99.7%. As an extractant for separating and recovering high purity butadiene from cracked C4 hydrocarbons, the recovery rate was 97%, and the purity of recovered butadiene was 99.7%. It was used as an extractant for recovering high purity isoprene from C5 hydrocarbons, and the recovery purity of isoprene was 99%; when used as aromatic extractant, because of its high solubility and low vapor pressure for aromatic hydrocarbons, the loss rate of extractant is low and the recovery rate of aromatic hydrocarbons is high. 3, reagent grade: Integrated circuits, hard disks and other requirements to strictly control the metal ions and fine particles of the industry, degreasing, dewaxing, polishing, rust, paint, etc, such as used as Photoresist removal liquid, IC semiconductor industry precision instruments, LCD liquid crystal materials, PCB Printed circuit board, hard disk cleaning; And artificial kidney functional membrane liquid, seawater desalination membrane liquid and other solvents produced in the pharmaceutical industry. is an excellent solvent, which is widely used as an extractant for aromatic extraction, lubricating oil refining, acetylene concentration, synthesis gas desulfurization, etc, N-methyl pyrrolidone is an excellent extraction solvent, widely used for aromatic extraction, acetylene concentration, the extraction agent in the process of butadiene separation and desulfurization of synthesis gas is also a solvent in the production of pesticides, engineering plastics, coatings, synthetic fibers, integrated circuits, etc., and can also be used as industrial detergents, dispersants, dyes, lubricating Oil antifreeze, etc. The product has low toxicity, rats oral LD50 is 7ml/kg. widely used in advanced lubricating oil refining, polymer synthesis, insulating materials, pesticides, pigments and cleaning agents, etc. used in aromatic extraction, purification of acetylene, olefins and diolefins; solvent for polymer and polymerization medium, such as polyamide, polyimide, polyphenylene sulfide and other engineering plastics and aramid fiber used as solvent and extractant. NMP is a polar aprotic solvent with low toxicity, The advantages of high boiling point, superior solubility, strong selectivity and good stability. Widely used in aromatic extraction; Acetylene, olefin, Diene purification. Solvents that are also used for the polymer and media for the polymerization reaction are required. Such as polyamide, polyimide, polyphenylene sulfide and other engineering plastics and aramid fiber. In addition, it is also used for insulating materials, pesticides, pigments and detergents.
production method	is derived from the reaction of γ-butyrolactone with methylamine. The first step of the reaction is the formation of 4-hydroxy-n-methylbutyramide from γ-butyrolactone and methylamine, and the second step is further dehydration to N-methylpyrrolidone. The two-step reaction can be carried out continuously in a tubular reactor with a molar ratio of γ-butyrolactone to methylamine of 1:1.15, a pressure of about 6MPA and a temperature of 250 °c. After completion of the reaction, the reaction mixture was concentrated and distilled under reduced pressure to obtain a finished product. The yield was 90%. If the kettle type counter is used for production, the amount of methylamine is 1.5-2.5 times of the theoretical amount, and the laboratory preparation is taken as an example. In a 280 ml autoclave, 2mol of γ-butyrolactone and 4 mol of liquid methylamine were added, and the mixture was sealed and heated at ° C. For 4 hours. After cooling, Excess methylamine was released, and distillation was carried out to collect the 201-202 ° C. Fraction to obtain about 180g of the product in a yield of about 90%. Raw material consumption (kg/g)γ-butyrolactone 980 methylamine (40%) 860
category	flammable liquid
toxicity grade	poisoning
Acute toxicity	oral-rat LD50: 3914 mg/kg; Oral-mouse LD50: 5130 mg/kg
stimulation data	eye-rabbit 100 mg moderate
flammability hazard characteristics	flammable in open flame, high temperature, strong oxidant; thermal decomposition of toxic nitric oxide gas
storage and transportation characteristics	The package is complete, light, light; The warehouse is ventilated, away from open flame, high temperature, separate from oxidant
fire extinguishing agent	foam, carbon dioxide, dry powder, sand
Occupational Standard	TWA 100 PPM (400 mg/m3); sel 100 mg/m3
spontaneous combustion temperature	518 ° F.
toxic substance data	information provided by: pubchem.ncbi.nlm.nih.gov (external link)

Last Update：2024-04-09 15:16:53

JIANGSU BSECHEM CHEMICAL TECHNOLOGY CO., LTD.

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Product Name: 1-Methyl-2-pyrrolidinone Request for quotation
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Jiangsu Pules Biotechnology Co.,Ltd.

Name	1-Methyl-2-pyrrolidinone
Synonyms	NMP NMP-T NMP-EL M-PYROL(R) N-METHYLPYROLIDONE N-Methylpyrrolidone N-Methyl pyrrolidone N-Methyl-pyrrolidone N-METHYLPYRROLIDNONE N-METHYLPYRROLIDINONE 1-Methyl-2-pyrrolidone N-METHYLPYRROLID-2-ONE N-Methyl-2-pyrrolidone 1-METHYL-2-PYRROLIDINONE N-Methyl-2-pyrrolidinone 1-Methyl-2-pyrrolidinone 1-Methyl-2-pyrrolidinone, anhydrous N-Methyl-2-pyrrolidone Manufacturer N-Methyl-2-pyrrolidinone 872-50-4 NMP 1-Methyl-2-pyrrolidinone 872-50-4 NMP N-Methyl-2-pyrrolidinone 1-METHYL-2-PYRROLIDONE, REAGENT (ACS)1-METHYL-2-PYRROLIDONE, REAGENT (ACS)1-METHYL-2-PYRROLIDONE, REAGENT (ACS)
CAS	872-50-4 2687-44-7
EINECS	212-828-1
InChI	InChI=1/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3
InChIKey	SECXISVLQFMRJM-UHFFFAOYSA-N

2687-44-7

1-Methyl-2-pyrrolidinone

CAS: 872-50-4;2687-44-7

Molecular Formula: C5H9NO

2687-44-7 - Names and Identifiers

2687-44-7 - Physico-chemical Properties

2687-44-7 - Risk and Safety

2687-44-7 - Upstream Downstream Industry

2687-44-7 - Nature

Open Data Verified Data

2687-44-7 - Quality Standard

Open Data Verified Data

2687-44-7 - Preparation Method

Open Data Verified Data

2687-44-7 - Use

Open Data Verified Data

2687-44-7 - Safety

Open Data Verified Data

2687-44-7 - Reference Information

Supplier List

2687-44-7 Request for Quotation

1-Methyl-2-pyrrolidinone

CAS: 872-50-4;2687-44-7

Molecular Formula: C5H9NO

2687-44-7 - Names and Identifiers

2687-44-7 - Physico-chemical Properties

2687-44-7 - Risk and Safety

2687-44-7 - Upstream Downstream Industry

2687-44-7 - Nature

Open Data Verified Data

2687-44-7 - Quality Standard

Open Data Verified Data

2687-44-7 - Preparation Method

Open Data Verified Data

2687-44-7 - Use

Open Data Verified Data

2687-44-7 - Safety

Open Data Verified Data

2687-44-7 - Reference Information

Supplier List

2687-44-7