268734-29-8

268734-29-8 - Names and Identifiers

Name	Fmoc-(R)-3-Amino-4-(2-chloro-phenyl)-butyric acid
Synonyms	Fmoc-D-β-HoPhe(2-Cl)-OH FMOC-D-BETA-HOPHE(2-CL)-OH FMOC-D-PHE(2-CL)-(C*CH2)OH FMOC-2-CHLORO-D-BETA-HOMOPHENYLALANINE FMOC-(R)-3-AMINO-4-(2-CHLOROPHENYL)BUTANOIC ACID FMOC-(R)-3-AMINO-4-(2-CHLORO-PHENYL)-BUTYRIC ACID Fmoc-(R)-3-Amino-4-(2-chloro-phenyl)-butyric acid (R)-N-(9-Fluorenylmethyloxycarbonyl)-3-amino-4-(2-chlorophenyl)butyric acid FMoc-2-chloro-D-β-hoMophenylalanine FMoc-(R)-3-aMino-4-(2-chlorophenyl)butyric acid
CAS	268734-29-8

268734-29-8 - Physico-chemical Properties

Molecular Formula	C25H22ClNO4
Molar Mass	435.9
Density	1.313±0.06 g/cm3(Predicted)
Boling Point	653.6±55.0 °C(Predicted)
pKa	4.34±0.10(Predicted)
Storage Condition	2-8°C

268734-29-8 - Risk and Safety

Hazard Class

IRRITANT

268734-29-8 - Introduction

Fmoc-(R)-3-Amino-4-(2-choro-phenyl)-butyric is an organic compound commonly used in the synthesis of polypeptides and proteins.

Nature:
Fmoc-(R)-3-Amino-4-(2-chloroform-phenyl)-butyric acid is a white crystalline solid, stable at ambient temperature. Its chemical formula is C20H17ClNO3 and its relative molecular mass is 355.8. It has good solubility in conventional solvents. This compound has a certain chirality and can have two stereoisomers, (R) or (S).

Use:
Fmoc-(R)-3-Amino-4-(2-chloroo-phenyl)-butyric acid is an important raw material for the synthesis of peptides and proteins. It is often used as a temporary protecting group for protecting amino acids, which can protect the amine group in the amino acid to ensure that the specific chemical reaction is carried out accurately during the synthesis.

Preparation Method:
Fmoc-(R)-3-Amino-4-(2-choro-phenyl)-butyric acid can be synthesized by a variety of methods. A common method is the reaction of 3-amino -4-(2-chlorophenyl) butanoic acid with Fmoc-Cl in the presence of sodium hydroxide to produce the desired product.

Safety Information:
Fmoc-(R)-3-Amino-4-(2-chloroo-phenyl)-butyric acid is generally not toxic and dangerous to humans and the environment under normal operating conditions. However, when handling the compound, it is recommended to wear appropriate protective equipment and avoid direct contact with the skin and eyes. At the same time, it should be operated in a well-ventilated place to avoid inhaling aerosols or dust. It is very important to follow the procedures for safe handling of chemicals.

Last Update：2024-04-10 22:29:15