269066-08-2
(2S)-4-[[4-[[1-(4,4-dimethyl-2,6-dioxo-cyclohexylidene)-3-methyl-butyl]amino]phenyl]methoxy]-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-butanoic acid
CAS: 269066-08-2
Molecular Formula: C39H42N2O8
269066-08-2 - Names and Identifiers
269066-08-2 - Physico-chemical Properties
| Molecular Formula | C39H42N2O8 |
| Molar Mass | 666.76 |
| Density | 1.264±0.06 g/cm3(Predicted) |
| Boling Point | 841.0±65.0 °C(Predicted) |
| Flash Point | 462.422°C |
| Vapor Presure | 0mmHg at 25°C |
| pKa | 3.51±0.23(Predicted) |
| Storage Condition | Inert atmosphere,2-8°C |
| Refractive Index | 1.608 |
269066-08-2 - Introduction
N-Fluorenylmethoxycarbonyl-L-aspartic acid (N-Fmoc-L-phenylalanine) is an organic compound with the chemical structure 4-[[4-[[1-(4, 4-Dimethyl-2, 6-dioxocyclohexylidene)-3-methylbutyl] amino]phenyl] methyl] Ester (((2S)-4-[[4-[[1-(4,4-dimethyl-2,6-dioxo-cyclohexylidene)-3-methyl-butyl]amino]phenyl]methoxy]-2-(phenyl)-4-oxo-butanoic acid).
Properties of the compound:
Appearance: White to light yellow solid
Molecular weight: 750.82g/mol
Melting point: About 150-160 ° C
Main uses of the compound:
1. N-Fmoc-L-phenylalanine is a common amino acid protecting group, commonly used in the synthesis of peptides and proteins.
2. It can also be used as an intermediate in drug synthesis, such as the preparation of amino acid derivatives.
Method:
N-Fmoc-L-phenylalanine can be prepared by reacting p-fluoronitrophenyl ketone with a Schigler amino acid (N-fluorenyl-L-phenylalanine). During the reaction, P-fluoronitrophenyl ketone first undergoes a nucleophilic substitution reaction with Schigler amino acid, and then the target product is obtained through oxidation, reduction and acylation reactions.
Safety Information:
N-Fmoc-L-phenylalanine currently have no clear safety information. However, since it is an organic compound, care should be taken to avoid contact with eyes and skin, and to avoid inhalation or ingestion. During use, please follow safe operating procedures, wear appropriate personal protective equipment, and ensure well-ventilated experimental conditions. In case of contact, rinse immediately with plenty of water. If discomfort occurs, seek medical attention.
Properties of the compound:
Appearance: White to light yellow solid
Molecular weight: 750.82g/mol
Melting point: About 150-160 ° C
Main uses of the compound:
1. N-Fmoc-L-phenylalanine is a common amino acid protecting group, commonly used in the synthesis of peptides and proteins.
2. It can also be used as an intermediate in drug synthesis, such as the preparation of amino acid derivatives.
Method:
N-Fmoc-L-phenylalanine can be prepared by reacting p-fluoronitrophenyl ketone with a Schigler amino acid (N-fluorenyl-L-phenylalanine). During the reaction, P-fluoronitrophenyl ketone first undergoes a nucleophilic substitution reaction with Schigler amino acid, and then the target product is obtained through oxidation, reduction and acylation reactions.
Safety Information:
N-Fmoc-L-phenylalanine currently have no clear safety information. However, since it is an organic compound, care should be taken to avoid contact with eyes and skin, and to avoid inhalation or ingestion. During use, please follow safe operating procedures, wear appropriate personal protective equipment, and ensure well-ventilated experimental conditions. In case of contact, rinse immediately with plenty of water. If discomfort occurs, seek medical attention.
Last Update：2024-04-09 21:04:16
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Product Name: FMOC-ASP(ODMAB)-OH Visit Supplier Webpage Request for quotation
CAS: 269066-08-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 269066-08-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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