Name | 2'-azido-2'-deoxyuridine |
Synonyms | N3-dU 2'-Az-dU 2'-N3-2'-dU 2'-AZIDO-2'-DU 2''-AZIDO-D-URIDINE 2'-azido-2'-deoxyuridine 2'-AZIDO-2'-DEOXYURIDINE Uridine,2'-azido-2'-deoxy- 2'-Azido-2'-deoxy-D-uridine 1-(2-azido-2-deoxypentofuranosyl)pyrimidine-2,4(1H,3H)-dione |
CAS | 26929-65-7 |
EINECS | 248-113-6 |
InChI | InChI=1/C9H11N5O5/c10-13-12-6-7(17)4(3-15)19-8(6)14-2-1-5(16)11-9(14)18/h1-2,4,6-8,15,17H,3H2,(H,11,16,18) |
Molecular Formula | C9H11N5O5 |
Molar Mass | 269.22 |
Melting Point | 149-153°C |
Appearance | powder to crystal |
Color | White to Almost white |
Maximum wavelength(λmax) | ['260nm(lit.)'] |
Storage Condition | 2-8°C |
In vitro study | 2'-Azido-2'-deoxyuridine (N3dUrd) has IC 50 s of >350 μM for ribonucleotide reductase activity in chinese hamster ovary (CHO) and 3T6 cell. |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S24/25 - Avoid contact with skin and eyes. S22 - Do not breathe dust. |
WGK Germany | 3 |
FLUKA BRAND F CODES | 8-10-21 |
HS Code | 29349990 |
Biological activity | 2 '-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase (ribonucleotide reductase) inhibitor. 2 '-Azido-2'-deoxyuridine has anticancer activity. |