27-acetoxy-5β,6β-epoxy-4β-hydroxy-1-oxo-witha-2,24-dienolide - Names and Identifiers
Name | 27-O-acetyl-withaferin A
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Synonyms | 27-O-acetyl-withaferin A 27-O-ACETYL-WITHAFERIN A 27-acetoxy-5β,6β-epoxy-4β-hydroxy-1-oxo-witha-2,24-dienolide Ergosta-2,24-dien-26-oic acid, 27-(acetyloxy)-5,6-epoxy-4,22-dihydroxy-1-oxo-, δ-lactone, (4β,5β,6β,22R)-
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CAS | 1214886-35-7
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27-acetoxy-5β,6β-epoxy-4β-hydroxy-1-oxo-witha-2,24-dienolide - Physico-chemical Properties
Molecular Formula | C30H40O7
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Molar Mass | 512.64 |
Density | 1.26±0.1 g/cm3(Predicted) |
Boling Point | 679.1±55.0 °C(Predicted) |
pKa | 13.49±0.70(Predicted) |
Storage Condition | 2-8℃ |
27-acetoxy-5β,6β-epoxy-4β-hydroxy-1-oxo-witha-2,24-dienolide - Introduction
27-O-acetyl-withaferin A is A natural product, which belongs to the ketone composition of Rauvolfia. It is extracted from the Withania somnifera of the roots of Garcinia gambogia. The following are some information about the properties, uses, preparation and safety of the compound:
Nature:
-Appearance: 27-O-acetyl-withaferin A is A white or off-white crystalline solid.
-Solubility: It dissolves in some organic solvents, such as dimethyl sulfoxide and dichloromethane.
Use:
-Pharmacological effects: Studies have shown that 27-O-acetyl-withaferin A has A variety of biological activities, such as anti-inflammatory, anti-cancer, anti-oxidation, and protective effects on the central nervous system. It may have potential applications in cancer therapy, immune regulation and neuroprotection.
-Anti-cancer effect: Studies have shown that 27-O-acetyl-withaferin A can inhibit the proliferation and invasion of various types of tumor cells, and promote tumor cell apoptosis.
Method:
The preparation method of-27-O-acetyl-withaferin A usually involves the isolation and purification of the compound from Withania somnifera. As the study of this compound deepens, researchers are developing more efficient synthetic routes.
Safety Information:
-Information on the toxicity and safety of 27-O-acetyl-withaferin A is very limited. No detailed studies on its toxicity or side effects in humans have been reported. Therefore, it is necessary to take appropriate laboratory safety measures when using this compound and to follow relevant safe handling guidelines.
Please note: The above information is for reference only. If necessary, please consult A professional before using 27-O-acetyl-withaferin A, and operate under suitable conditions.
Last Update:2024-04-09 20:48:19