2836-40-0
2-chloro-N-[4-chloro-2-(2-fluorobenzoyl)phenyl]acetamide
CAS: 2836-40-0
Molecular Formula: C15H10Cl2FNO2
2836-40-0 - Names and Identifiers
| Name | 2-chloro-N-[4-chloro-2-(2-fluorobenzoyl)phenyl]acetamide |
| Synonyms | 2,4'-Dichloro-2'-(2-fluorobenzoyl)acetoanilide 2-(2-Chloroacetamido)-5-chloro-2'-fluorobenzophenone 2-chloro-N-[4-chloro-2-(2-fluorobenzoyl)phenyl]acetamide |
| CAS | 2836-40-0 |
| EINECS | 220-625-4 |
| InChI | InChI=1/C15H10Cl2FNO2/c16-8-14(20)19-13-6-5-9(17)7-11(13)15(21)10-3-1-2-4-12(10)18/h1-7H,8H2,(H,19,20) |
2836-40-0 - Physico-chemical Properties
| Molecular Formula | C15H10Cl2FNO2 |
| Molar Mass | 326.15 |
| Density | 1.429g/cm3 |
| Boling Point | 565.7°C at 760 mmHg |
| Flash Point | 296°C |
| Vapor Presure | 8.07E-13mmHg at 25°C |
| Storage Condition | 2-8°C |
| Refractive Index | 1.619 |
2836-40-0 - Introduction
2-chloroo-n-[4-chloro-2-(2-fluorobenzoyl)phenyl]acetamide is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White crystalline solid
-Molecular formula: C16H11Cl2FNO2
-Molecular weight: 349.17g/mol
-Melting Point: about 180-182 ° C
-Solubility: Soluble in common organic solvents (such as ethanol, acetone, dimethyl sulfoxide)
Use:
2-chloroo-n-[4-chloro-2-(2-fluorobenzoyl)phenyl]acetamide is an intermediate used in drug synthesis. It can be used to synthesize organic molecules with biological activity, for example, for the preparation of drugs with antibacterial, anti-tumor and other activities.
Method:
The preparation of 2-chloroo-n-[4-chloro-2-(2-fluorobenzoyl)phenyl]acetamide can be carried out by the following steps:
1. P-fluorobenzoic acid reacts with sodium hypochlorite to generate 2-chloro -4 '-fluorobenzoic acid.
2.2-chloro -4 '-fluorobisbenzoic acid reacts with sodium hypochlorite and oxidant to generate 2-chloro -4'-fluorobisbenzoyl chloride.
3.2-chloro-4 '-fluorobisbenzoyl chloride is reacted with an amino acid having chlorohydrin to produce 2-chloroo-n-[4-chloro-2-(2-fluorobenzoyl)phenyl]acetamide.
Safety Information:
2-chloroo-n-[4-chloro-2-(2-fluorobenzoyl)phenyl]acetamide is a chemical that requires the following safety precautions:
-Avoid inhaling, chewing or swallowing. Wear protective gloves, protective glasses and protective mask when using.
-Avoid contact with skin and eyes. In case of contact, flush with plenty of water and seek medical help.
-Operate in a well-ventilated place to avoid prolonged exposure to the smell of the substance.
-Store chemicals in a dry, cool, ventilated place, away from fire and flammable substances.
-In the use and handling of the chemical, the relevant safety procedures and regulations should be strictly observed.
Nature:
-Appearance: White crystalline solid
-Molecular formula: C16H11Cl2FNO2
-Molecular weight: 349.17g/mol
-Melting Point: about 180-182 ° C
-Solubility: Soluble in common organic solvents (such as ethanol, acetone, dimethyl sulfoxide)
Use:
2-chloroo-n-[4-chloro-2-(2-fluorobenzoyl)phenyl]acetamide is an intermediate used in drug synthesis. It can be used to synthesize organic molecules with biological activity, for example, for the preparation of drugs with antibacterial, anti-tumor and other activities.
Method:
The preparation of 2-chloroo-n-[4-chloro-2-(2-fluorobenzoyl)phenyl]acetamide can be carried out by the following steps:
1. P-fluorobenzoic acid reacts with sodium hypochlorite to generate 2-chloro -4 '-fluorobenzoic acid.
2.2-chloro -4 '-fluorobisbenzoic acid reacts with sodium hypochlorite and oxidant to generate 2-chloro -4'-fluorobisbenzoyl chloride.
3.2-chloro-4 '-fluorobisbenzoyl chloride is reacted with an amino acid having chlorohydrin to produce 2-chloroo-n-[4-chloro-2-(2-fluorobenzoyl)phenyl]acetamide.
Safety Information:
2-chloroo-n-[4-chloro-2-(2-fluorobenzoyl)phenyl]acetamide is a chemical that requires the following safety precautions:
-Avoid inhaling, chewing or swallowing. Wear protective gloves, protective glasses and protective mask when using.
-Avoid contact with skin and eyes. In case of contact, flush with plenty of water and seek medical help.
-Operate in a well-ventilated place to avoid prolonged exposure to the smell of the substance.
-Store chemicals in a dry, cool, ventilated place, away from fire and flammable substances.
-In the use and handling of the chemical, the relevant safety procedures and regulations should be strictly observed.
Last Update：2024-04-09 19:05:48
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CAS: 2836-40-0
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