290297-24-4
6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-amine
CAS: 290297-24-4
Molecular Formula: C17H22N4
290297-24-4 - Names and Identifiers
| Name | 6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-amine |
| Synonyms | Netupitant Impurity 8 TriHCl 6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-amine |
| CAS | 290297-24-4 |
290297-24-4 - Physico-chemical Properties
| Molecular Formula | C17H22N4 |
| Molar Mass | 282.38 |
| Use | Intermediate |
290297-24-4 - Introduction
N'-1 (6-(4-methylpiperazin-1-yl)-4-(o-tolyl) pyridin -3-amine) is an intermediate of netupitan, its chemical structure is 6-(4-methylpiperazin-1-yl)-4-(o-tolyl) pyridin -3-amine. Here is some information about the intermediate:
Nature:
-Appearance: White to light yellow crystalline powder.
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide (DMSO), dimethylformamide (DMF) and methanol.
-Melting point: approximately 120-125°C.
Use:
N'-1 (6-(4-methylpiperazin-1-yl)-4-(o-tolyl) pyridine-3-amine) is an intermediate of netupitan, can be used in the preparation of netupitant synthesis of this drug.
Method:
6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-amine(6-(4-methylpiperazin-1-yl)-4-(o-tolyl) pyridine-3-amine) can be prepared by the condensation reaction of pyridine-2, 6-dione and 4-amino -1, 2-dimethylbenzene. The specific synthetic steps and conditions may vary according to the specific research and development of the laboratory or pharmaceutical company.
Safety Information:
Since N'-1 (6-(4-methylpiperazin-1-yl)-4-(o-tolyl) pyridin -3-amine) it is an intermediate of netupitan, and relevant safety information may not have specific information for reference. However, as intermediates of chemical substances, they should generally be handled and stored according to relevant laboratory safety procedures to minimize potential hazards. During use, please follow appropriate personal protective measures, avoid contact with skin and eyes, and ensure that you operate under well-ventilated conditions.
Nature:
-Appearance: White to light yellow crystalline powder.
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide (DMSO), dimethylformamide (DMF) and methanol.
-Melting point: approximately 120-125°C.
Use:
N'-1 (6-(4-methylpiperazin-1-yl)-4-(o-tolyl) pyridine-3-amine) is an intermediate of netupitan, can be used in the preparation of netupitant synthesis of this drug.
Method:
6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-amine(6-(4-methylpiperazin-1-yl)-4-(o-tolyl) pyridine-3-amine) can be prepared by the condensation reaction of pyridine-2, 6-dione and 4-amino -1, 2-dimethylbenzene. The specific synthetic steps and conditions may vary according to the specific research and development of the laboratory or pharmaceutical company.
Safety Information:
Since N'-1 (6-(4-methylpiperazin-1-yl)-4-(o-tolyl) pyridin -3-amine) it is an intermediate of netupitan, and relevant safety information may not have specific information for reference. However, as intermediates of chemical substances, they should generally be handled and stored according to relevant laboratory safety procedures to minimize potential hazards. During use, please follow appropriate personal protective measures, avoid contact with skin and eyes, and ensure that you operate under well-ventilated conditions.
Last Update：2024-04-09 21:04:16
