Name | 2-Amino-5-methylbenzoic acid |
Synonyms | 6-Amino-m-toluic acid 2-amino-5-methylbenzoate 5-Methylanthranilic acid 2-Carboxy-4-methylaniline 2-AMino-5-Methylbenzoic aci 2-Amino-5-methylbenzoic acid 6-Amino-m-toluic Acid5-Methylanthranilic Acid 5-Methylanthranilic acid, 2-Carboxy-4-methylaniline, 6-Amino-m-toluic acid |
CAS | 2941-78-8 |
EINECS | 220-932-3 |
InChI | InChI=1/C8H9NO2/c1-5-2-3-7(9)6(4-5)8(10)11/h2-4H,9H2,1H3,(H,10,11)/p-1 |
InChIKey | NBUUUJWWOARGNW-UHFFFAOYSA-N |
Molecular Formula | C8H9NO2 |
Molar Mass | 151.16 |
Density | 1.2023 (rough estimate) |
Melting Point | 175 °C (dec.) (lit.) |
Boling Point | 273.17°C (rough estimate) |
Flash Point | 145.3°C |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Vapor Presure | 0.000171mmHg at 25°C |
Appearance | Solid |
Color | Off-white to beige |
BRN | 1101527 |
pKa | 2.27±0.10(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Refractive Index | 1.5810 (estimate) |
MDL | MFCD00007909 |
Physical and Chemical Properties | Appearance: light yellow crystal Melting Point: 181-183 ℃ |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection |
WGK Germany | 3 |
FLUKA BRAND F CODES | 10 |
HS Code | 29224999 |
Hazard Class | IRRITANT |
NIST chemical information | Information provided by: webbook.nist.gov (external link) |
Uses | 2-amino-5-methylbenzoic acid is a compound that can be used in organic synthesis. |
application | 2-amino -5-methylbenzoic acid is an organic synthesis intermediate and a pharmaceutical intermediate, which can be used in laboratory research and development processes and chemical and pharmaceutical synthesis processes. |
Synthetic route | Using p-methylaniline as raw material, it reacts with chloral hydrate and hydroxylamine hydrochloride to prepare 5-methylisatin, and then reacts at room temperature in H2O2/NaOH system to obtain 2-amino-5-methylbenzoic acid. Based on p-methylaniline, the total yield is 43.4%. |