3(R)-HYDROXYMETHYL-1,2,3,4-TETRAHYDRO-ISOQUINOLINE

3(R)-HYDROXYMETHYL-1,2,3,4-TETRAHYDRO-ISOQUINOLINE - Names and Identifiers

Name	(3R)-1,2,3,4-tetrahydroisoquinolin-3-ylmethanol
Synonyms	(R)-1,2,3,4-Tetrahydroisoquinolyl-methan-3-ol (3R)-1,2,3,4-tetrahydroisoquinolin-4-ylMethanol (3R)-1,2,3,4-Tetrahydroisoquinolin-3-ylmethanol (3R)-1,2,3,4-tetrahydroisoquinolin-3-ylmethanol (R)-(1,2,3,4-Tetrahydroisoquinolin-3-Yl)-Methanol (R)-(1,2,3,4-TETRAHYDROISOQUINOLIN-3-YL)-METHANOL (R)-(+)-1,2,3,4-Tetrahydro-3-isoquinolinemethanol (R)-(1,2,3,4-tetrahydroisoduinolin-3-yl)-Methanol 3-isoquinolinemethanol, 1,2,3,4-tetrahydro-, (3R)- 3(R)-HYDROXYMETHYL-1,2,3,4-TETRAHYDRO-ISOQUINOLINE 2-chloro-4-[[2-(diethylamino)-5-methoxyphenyl]methyl]-N,N-dimethylaniline
CAS	62855-02-1
InChI	InChI=1/C10H13NO/c12-7-10-5-8-3-1-2-4-9(8)6-11-10/h1-4,10-12H,5-7H2/t10-/m1/s1

3(R)-HYDROXYMETHYL-1,2,3,4-TETRAHYDRO-ISOQUINOLINE - Physico-chemical Properties

Molecular Formula	C10H13NO
Molar Mass	163.22
Density	1.081±0.06 g/cm3(Predicted)
Boling Point	307.9±27.0 °C(Predicted)
Flash Point	147°C
Vapor Presure	0.000305mmHg at 25°C
Appearance	White powder
Color	White
pKa	14.57±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Refractive Index	1.549
MDL	MFCD02684327

3(R)-HYDROXYMETHYL-1,2,3,4-TETRAHYDRO-ISOQUINOLINE - Risk and Safety

Safety Description	24/25 - Avoid contact with skin and eyes.
HS Code	29339900

3(R)-HYDROXYMETHYL-1,2,3,4-TETRAHYDRO-ISOQUINOLINE - Introduction

(3R)-1,2,3, Br is an organic compound whose chemical formula is C10H13NO. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: Colorless to light yellow solid
-Melting point: about 60-65 ℃
-Thermal stability: Soluble in a variety of organic solvents, such as alcohols and ethers
-Optical rotation: it is dextrorotatory, and its symbol is ()
-Molecular structure: has a tetrahydroisoquinoline ring and a hydroxymethyl functional group

Use:
-Used in organic synthesis: As a chiral intermediate, it can be used in various organic synthesis reactions, especially the synthesis of Strick compounds (Strick compounds).
-Drug research: In drug research, it can be used as an intermediate for the synthesis of chiral drugs or as a chiral catalyst.

Preparation Method:
The preparation method of (3R)-1,2,3, can be achieved by chiral redox reaction. A common synthesis method is the use of triphenylphosphine (triphenylphosphine) induced cyclopentadiene redox reaction, after a multi-step reaction to obtain the target product.

Safety Information:
The safety of this compound has not been reported in detail. In general, however, proper laboratory practices need to be followed when handling organic compounds to ensure safety. Direct contact with skin and eyes should be avoided, and use in a well-ventilated place should be ensured. If exposed or inhaled, wash or seek medical help. Appropriate personal protective equipment should always be worn when performing chemical synthesis or laboratory operations.

Last Update：2024-04-09 20:45:29