3,3,3-trifluoro-propylamin
3,3,3-trifluoropropan-1-amine
CAS: 460-39-9
Molecular Formula: C3H6F3N
3,3,3-trifluoro-propylamin - Names and Identifiers
3,3,3-trifluoro-propylamin - Physico-chemical Properties
| Molecular Formula | C3H6F3N |
| Molar Mass | 113.08 |
| Density | 1.152±0.06 g/cm3(Predicted) |
| Boling Point | 67 °C |
| Vapor Presure | 616mmHg at 25°C |
| pKa | 8.18±0.10(Predicted) |
| Refractive Index | 1.328 |
3,3,3-trifluoro-propylamin - Risk and Safety
| Hazard Symbols | C - Corrosive |
| Risk Codes | 41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. |
| Hazard Note | Corrosive |
3,3,3-trifluoro-propylamin - Reference Information
| application | 3,3, 3-trifluoropropylamine plays a very important role in the pharmaceutical, pesticide and chemical industries as chiral amines. They are usually used as intermediates or synthetic monomers to prepare various physiologically active substances such as pharmaceutical active substances. 3,3, 3-trifluoropropylamine transaminases can be divided into 5 categories: aspartate transaminase, aromatic transaminase, ω-transaminase, branched chain transaminase and D-transaminase. Since ω-transaminase can catalyze some specific substrates, it has better industrial application value. |
| preparation | adding 0.25 mgω-TA, 5 μmol trifluoroacetone, 15 μmol-aspartic acid and 0.1 μmolPLP to 2mL of 20 mMpH8.0 phosphate buffer, reacting at 25 ℃ for 1h to obtain 3,3, 3-trifluoropropylamine with a conversion rate of 97.0%. |
Last Update：2024-04-09 21:04:16
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