3,4-Difluoro-2-hydroxybenzaldehyde

3,4-Difluoro-2-hydroxybenzaldehyde - Names and Identifiers

Name	3,4-difluoro-2-hydroxy-benzaldehyde
Synonyms	3,4-difluorosalicyladehyde 3,4-Difluoro-2-hydroxybenzaldehyde 3,4-difluoro-2-hydroxy-benzaldehyde Benzaldehyde, 3,4-difluoro-2-hydroxy- Benzaldehyde, 3,4-difluoro-2-hydroxy- (9CI)
CAS	502762-95-0
EINECS	642-754-9
InChI	InChI=1/C7H4F2O2/c8-5-2-1-4(3-10)7(11)6(5)9/h1-3,11H

3,4-Difluoro-2-hydroxybenzaldehyde - Physico-chemical Properties

Molecular Formula	C7H4F2O2
Molar Mass	158.1
Density	1.464±0.06 g/cm3(Predicted)
Boling Point	192.2±35.0 °C(Predicted)
Flash Point	70.061°C
Vapor Presure	0.355mmHg at 25°C
pKa	5.92±0.15(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.559

3,4-Difluoro-2-hydroxybenzaldehyde - Introduction

3, is an organic compound with the chemical formula C7H4F2O2. The following is a description of its nature, use, preparation and safety information:

1. nature:
-Appearance: Colorless crystalline solid;
-Solubility: Soluble in organic solvents such as alcohols, ethers and ketones, insoluble in water;
-Melting point: about 57-58°C;
-Boiling point: about 201-203°C.

2. use:
3, is widely used in organic synthesis as an intermediate for the preparation of other compounds. It can participate in the esterification of alcohols and can also be used to prepare biologically active compounds, such as drugs and pesticides.

3. Preparation method:
3, can generally be synthesized by the reaction of salicylaldehyde and hydrogen fluoride or fluoride. The specific preparation method is as follows:
a. Under alkaline conditions, salicylaldehyde reacts with hydrogen fluoride to generate 3, Ni.

4. Safety Information:
- 3, should be stored in a cool, dry place, avoid direct sunlight;
-use should wear protective glasses and gloves, avoid inhalation or contact with the skin;
- **3, irritating, harmful to eyes, skin and respiratory system. **In case of careless contact, rinse immediately with plenty of water and seek medical assistance;
-When performing laboratory synthesis, it should be carried out in a well-ventilated environment;
-Avoid contact with moist substances, oxidants, etc.

**Note: When using or handling this compound, please follow appropriate laboratory procedures and operate in accordance with relevant regulations. * *

Last Update：2024-04-09 02:00:46