3,5-DI(TRIFLUOROMETHYL)PHENYLHYDRAZINE

3,5-DI(TRIFLUOROMETHYL)PHENYLHYDRAZINE - Names and Identifiers

Name	3,5-Bis(trifluoromethyl)phenylhydrazine
Synonyms	2,3-difluoro-4-methoxybenzamide 3,5-DI(TRIFLUOROMETHYL)PHENYLHYDRAZINE 3,5-di(Trifluoromethyl)phenylhydrazine 3,5-BIS(TRIFLUOROMETHYL)PHENYLHYDRAZINE 3,5-Bis(trifluoromethyl)phenylhydrazine [3,5-Bis(trifluoromethyl)phenyl]hydrazine 1-[3,5-di(trifluoromethyl)phenyl]hydrazine 1-[3,5-Bis(trifluoromethyl)phenyl]hydrazine Hydrazine, [3,5-bis(trifluoromethyl)phenyl]- 3,5-Bis(trifluoromethyl)phenylhydrazinehydrochlor
CAS	886-35-1
InChI	InChI=1/C8H7F2NO2/c1-13-5-3-2-4(8(11)12)6(9)7(5)10/h2-3H,1H3,(H2,11,12)

3,5-DI(TRIFLUOROMETHYL)PHENYLHYDRAZINE - Physico-chemical Properties

Molecular Formula	C8H6F6N2
Molar Mass	244.14
Density	1.497±0.06 g/cm3(Predicted)
Melting Point	80 °C
Boling Point	196.5±40.0 °C(Predicted)
Flash Point	81.6°C
Water Solubility	Sparingly Soluble is water.
Vapor Presure	0.184mmHg at 25°C
BRN	1843213
pKa	4.10±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.507
MDL	MFCD00051606

3,5-DI(TRIFLUOROMETHYL)PHENYLHYDRAZINE - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
Hazard Class	IRRITANT

3,5-DI(TRIFLUOROMETHYL)PHENYLHYDRAZINE - Introduction

3,5-Bis(trifluoromethyl)phenylhydrazine is an organic compound with the chemical formula C8H5F6N2. It is a colorless crystalline solid at room temperature.

Nature:
1. Melting point: 56-59°C
2. boiling point: 224°C (decomposition)
3. Solubility: Soluble in organic solvents such as ethanol, ether and chloroform, slightly soluble in water.

Use:
3,5-Bis(trifluoromethyl)phenylhydrazine has good reactivity and stability, and is commonly used in alkylation reaction, cyclization reaction and ketone reduction reaction in organic synthesis. It can be used as a catalyst, reagent or intermediate in the field of pesticide, medicine and chemical research.

Preparation Method:
Common preparation methods include:
1. In the presence of benzenecesium carbonate, the methylene group phenylhydrazine by oxidation of 3,5-Bis(trifluoromethyl) by tert-butanol peroxide.
2. Under the catalysis of hydrogen peroxide, it is prepared by the reduction of p-nitrobenzene ammonia.

Safety Information:
1. 3,5-Bis(trifluoromethyl)phenylhydrazine may be irritating to eyes, skin and respiratory tract, and protective equipment should be worn during operation.
2. Must operate in a well-ventilated environment to avoid inhalation, ingestion or contact with skin.
3. should be stored away from combustibles and strong oxidants.
4. in case of leakage, attention should be paid to avoid contact with the fire source and clean it up in time.

Please note that when conducting experiments or the use of chemical agents, please ensure that all safe operating instructions and appropriate laboratory rules and regulations are understood and followed.

Last Update：2024-04-09 15:18:00