3,5-DICHLORO-4-FLUOROBENZOTRIFLUORIDE
3,5-Dichloro-4-fluorobenzotrifluoride
CAS: 77227-81-7
Molecular Formula: C7H2Cl2F4
3,5-DICHLORO-4-FLUOROBENZOTRIFLUORIDE - Names and Identifiers
3,5-DICHLORO-4-FLUOROBENZOTRIFLUORIDE - Physico-chemical Properties
| Molecular Formula | C7H2Cl2F4 |
| Molar Mass | 232.99 |
| Density | 1.555 g/mL at 25 °C (lit.) |
| Boling Point | 166-168 °C (lit.) |
| Flash Point | 164°F |
| Vapor Presure | 1.54mmHg at 25°C |
| BRN | 6199573 |
| Storage Condition | Room Temprature |
| Refractive Index | n20/D 1.462(lit.) |
3,5-DICHLORO-4-FLUOROBENZOTRIFLUORIDE - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| UN IDs | UN 2810 6.1/PG 3 |
| WGK Germany | 3 |
| HS Code | 29039990 |
| Hazard Class | IRRITANT |
3,5-DICHLORO-4-FLUOROBENZOTRIFLUORIDE - Reference Information
| application | 2,6-dichloro-p-trifluoromethylaniline is a chemical intermediate of medicine and pesticide, which is widely used in medicine, pesticide and other fields. |
| preparation | in a three-port reaction bottle equipped with a stirrer, a reflux condenser tube and a temperature of 1L, 200g 3,4, 5-trichlorotrifluorotoluene, 200g potassium fluoride and 500 ml sulfolane are added, then heated to 190 ℃, kept warm and stirred for 20 hours, and then cooled to 100 ℃. 200 grams of crude product (containing about 10% sulfolane) were steamed out under a pressure of 0.01MPa. Then raise the temperature to 150 ℃ and recover sulfolane under reduced pressure (which can be directly used in the next batch of reactions). 200 grams of crude 3, 5-dichloro-4-fluorotrifluorotoluene was directly used in the next ammoniation reaction. |
Last Update：2024-04-09 20:52:54
