3,6-diiodo-1H-indazole - Names and Identifiers
Name | 3,6-diiodo-1H-indazole
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Synonyms | 3,6-DIIODOINDAZOLE Axitinib Impurity 29 3,6-diiodo-1H-indazole 3,6-diiodo-2H-indazole 3,6-DIIODO (1H)INDAZOLE 1H-Indazole, 3,6-diiodo- Axitinib Impurity 29 (3,6-Diiodo-2H-Indazole)
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CAS | 319472-78-1
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InChI | InChI=1/C7H4I2N2/c8-4-1-2-5-6(3-4)10-11-7(5)9/h1-3H,(H,10,11) |
3,6-diiodo-1H-indazole - Physico-chemical Properties
Molecular Formula | C7H4I2N2
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Molar Mass | 369.93 |
Density | 2.656 |
Melting Point | >210°C (dec.) |
Boling Point | 434.6±25.0 °C(Predicted) |
Flash Point | 216.629°C |
Solubility | DMSO (Slightly), Methanol (Sparingly) |
Vapor Presure | 0mmHg at 25°C |
Appearance | Solid |
Color | Yellow to Dark Orange |
pKa | 11.00±0.40(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Stability | Light Sensitive |
Refractive Index | 1.854 |
3,6-diiodo-1H-indazole - Introduction
3,6-diiodo-1h-indazole is an organic compound with the chemical formula C7H3I2N, which has blue crystals or powder form. The following is a description of the nature, use, preparation and safety information of 3,6-diiodo-1h-indazole:
1. Nature:
-Appearance: Blue crystal or powder
-Melting point: About 250 ℃
-Solubility: Slightly soluble in some organic solvents, such as dimethyl sulfoxide (DMSO) and Dimethyl Formamide (DMF)
2. Use:
-Chemical synthesis: As an intermediate in chemical reactions, it is used to synthesize other organic compounds.
-Pharmaceutical research: 3,6-diiodo-1h-indazole and its derivatives are used as potential bioactive compounds in the field of pharmaceutical research.
3. Preparation method:
-3,6-diiodo-1h-indazole can be prepared by the reaction of indazole and iodination. Alkaline conditions or electrophiles (such as I2) can be used in the reaction conditions.
-The specific synthesis method can be fine-tuned and improved as needed.
4. Safety Information:
-3,6-diiodo-1h-indazole's impact on human health and safety have not been fully studied, so it is necessary to take appropriate protective measures during operation.
-Do not inhale, ingest or contact with skin.
-Personal protective equipment such as goggles, gloves and lab coats should be worn during operation.
-Strictly control the temperature and reaction conditions during the experiment to ensure safe operation.
Last Update:2024-04-09 19:05:49