3-(1H-Tetraazol-1-yl)phenol
3-Tetrazol-1-yl-phenol
CAS: 125620-16-8
Molecular Formula: C7H6N4O
3-(1H-Tetraazol-1-yl)phenol - Names and Identifiers
3-(1H-Tetraazol-1-yl)phenol - Physico-chemical Properties
| Molecular Formula | C7H6N4O |
| Molar Mass | 162.15 |
| Storage Condition | 2-8℃ |
| Sensitive | Irritant |
| MDL | MFCD01860802 |
3-(1H-Tetraazol-1-yl)phenol - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
3-(1H-Tetraazol-1-yl)phenol - Introduction
3-Tetrazol-1-yl-phenol is an organic compound with the formula C7H5N5O. The following is a description of some of the properties, uses, preparation and safety information of 3-Tetrazol-1-yl-phenol:
Nature:
-Appearance: White crystalline solid.
-Melting point: about 140-144 degrees Celsius.
-Solubility: Slightly soluble in water, soluble in some organic solvents such as dimethyl sulfoxide and chloroform.
Use:
-Chemical reagents: 3-Tetrazol-1-yl-phenol can be used as reagents and raw materials in organic synthesis, such as for the synthesis of tetrazolium oxalate compounds and other organic compounds containing tetrazolium groups.
-Pharmaceutical field: It is also used as an intermediate for certain drugs, with antibacterial, antiviral and anti-inflammatory effects.
Preparation Method:
3-Tetrazol-1-yl-phenol can be synthesized by the following steps:
1. Combine phenol and anhydrous tetramethyl sulfoxide and heat to reaction temperature.
2. Nitric acid and sulfuric acid were added dropwise to the mixture, and the reaction was continued by heating.
3. After completion of the reaction, the reaction mixture was cooled to obtain 3-Tetrazol-1-yl-phenol.
Safety Information:
-Dust from 3-Tetrazol-1-yl-phenol may be irritating to the eyes, skin and respiratory system. Use should wear appropriate protective measures to avoid direct contact.
-When handling or storing the compound, care should be taken to protect it from moisture, heat, open flame and strong light.
-It should be stored in a dry, clean, cool place, separate from oxidants and acids.
-Please refer to the safety instructions for the relevant chemicals and follow the corresponding safety procedures.
Nature:
-Appearance: White crystalline solid.
-Melting point: about 140-144 degrees Celsius.
-Solubility: Slightly soluble in water, soluble in some organic solvents such as dimethyl sulfoxide and chloroform.
Use:
-Chemical reagents: 3-Tetrazol-1-yl-phenol can be used as reagents and raw materials in organic synthesis, such as for the synthesis of tetrazolium oxalate compounds and other organic compounds containing tetrazolium groups.
-Pharmaceutical field: It is also used as an intermediate for certain drugs, with antibacterial, antiviral and anti-inflammatory effects.
Preparation Method:
3-Tetrazol-1-yl-phenol can be synthesized by the following steps:
1. Combine phenol and anhydrous tetramethyl sulfoxide and heat to reaction temperature.
2. Nitric acid and sulfuric acid were added dropwise to the mixture, and the reaction was continued by heating.
3. After completion of the reaction, the reaction mixture was cooled to obtain 3-Tetrazol-1-yl-phenol.
Safety Information:
-Dust from 3-Tetrazol-1-yl-phenol may be irritating to the eyes, skin and respiratory system. Use should wear appropriate protective measures to avoid direct contact.
-When handling or storing the compound, care should be taken to protect it from moisture, heat, open flame and strong light.
-It should be stored in a dry, clean, cool place, separate from oxidants and acids.
-Please refer to the safety instructions for the relevant chemicals and follow the corresponding safety procedures.
Last Update：2024-04-09 15:18:10
