3-(2-Chloropyrimidin-4-yl)-1-cyclopropyl-1H-indole - Names and Identifiers
3-(2-Chloropyrimidin-4-yl)-1-cyclopropyl-1H-indole - Physico-chemical Properties
Molecular Formula | C15H12ClN3
|
Molar Mass | 269.73 |
Density | 1.42±0.1 g/cm3(Predicted) |
Boling Point | 526.7±33.0 °C(Predicted) |
pKa | -0.92±0.31(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Physical and Chemical Properties | Storage conditions Inert atmosphere,2-8°C acidity coefficient (pKa) -0.92±0.31(Predicted) |
3-(2-Chloropyrimidin-4-yl)-1-cyclopropyl-1H-indole - Introduction
3-(2-Chloropyrimidin-4-yl)-1-cyclopropyl-1H-indole is an organic compound with the chemical formula C15H12ClN3. It is a white solid that can be dissolved in some organic solvents.
This compound has a variety of applications. First, it is an intermediate used in medical research. Secondly, due to its specific structure, it has anti-cancer and anti-inflammatory properties, so it may be used to develop anti-cancer and anti-inflammatory drugs. In addition, it is also used as a photosensitizer in photosensitive dyes and coatings.
The method for preparing 3-(2-Chloropyrimidin-4-yl)-1-cyclopropyl-1H-indole can generate N-cyclopropyl pyridinethione by reacting pyrimidine with cycloacetone, and then reacting with cyanogen chloride to generate 3-(chloropyrimidin-4-yl)-1-cyclopropyl pyridinethione. Finally, the target compound is produced by a hydrogenation reduction reaction.
safety issues should be paid attention to during use and handling. This compound may cause irritation to the eyes, skin and respiratory tract, and appropriate protective measures should be taken, such as wearing chemical protective glasses, face masks and gloves. In addition, contact with strong oxidants and heat sources should be avoided. During storage and handling, it should be stored in a dry, cool and well-ventilated place. If necessary, consult the relevant safety literature and follow the correct operating procedures.
Last Update:2024-04-09 21:00:56