3-(2-Hydroxyethyl)pyridine
3-(2-Hydroxyethyl)pyridine
CAS: 6293-56-7
Molecular Formula: C7H9NO
3-(2-Hydroxyethyl)pyridine - Names and Identifiers
3-(2-Hydroxyethyl)pyridine - Physico-chemical Properties
| Molecular Formula | C7H9NO |
| Molar Mass | 123.15 |
| Density | 1.090±0.06 g/cm3(Predicted) |
| Melting Point | 135 °C |
| Boling Point | 176 °C |
| Flash Point | 100.3°C |
| Vapor Presure | 0.0185mmHg at 25°C |
| pKa | 14.60±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.539 |
3-(2-Hydroxyethyl)pyridine - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| UN IDs | UN1760 |
| Hazard Note | Irritant |
3-(2-Hydroxyethyl)pyridine - Introduction
3-(2-Hydroxyethyl)pyridine is a chemical substance with the chemical formula C7H9NO. It has the following properties and uses:
Nature:
-Appearance: 3-(2-Hydroxyethyl)pyridine is a colorless to light yellow liquid.
-Solubility: It can be dissolved in water, alcohols and ether solvents.
-Melting point and boiling point: The melting point of 3-(2-Hydroxyethyl)pyridine is -43°C, and the boiling point is 194-195°C.
-Fragrance: It has a special smell.
Use:
-Chemical reagent: 3-(2-Hydroxyethyl)pyridine is commonly used as a catalyst and intermediate for organic synthesis reactions.
-Pharmaceutical field: It is often used to synthesize new drug molecules in drug research and development.
-Surfactant: It is used as a surfactant in certain cosmetics and personal care products.
Preparation Method:
The preparation of 3-(2-Hydroxyethyl)pyridine can be carried out by the following steps:
1.2-pyridinecarboxaldehyde and ethylene glycol reaction to generate 2-(2-hydroxyethyl) pyridine.
2.2-(2-hydroxyethyl) pyridine reacts with hydrogen bromide under alkaline conditions to generate 3-(2-Hydroxyethyl)pyridine.
3. Filtration and rectification to obtain pure product.
Safety Information:
- 3-(2-Hydroxyethyl)pyridine is an organic solvent, so care should be taken to avoid open flames to prevent fire.
-Wear appropriate protective equipment such as chemical gloves and safety glasses when in use.
-Avoid skin contact and inhalation of vapors to avoid allergies or other health problems.
-Please make sure to operate in a well-ventilated area when using.
-Immediately after contact with skin or eyes, rinse with plenty of water and seek medical assistance.
Nature:
-Appearance: 3-(2-Hydroxyethyl)pyridine is a colorless to light yellow liquid.
-Solubility: It can be dissolved in water, alcohols and ether solvents.
-Melting point and boiling point: The melting point of 3-(2-Hydroxyethyl)pyridine is -43°C, and the boiling point is 194-195°C.
-Fragrance: It has a special smell.
Use:
-Chemical reagent: 3-(2-Hydroxyethyl)pyridine is commonly used as a catalyst and intermediate for organic synthesis reactions.
-Pharmaceutical field: It is often used to synthesize new drug molecules in drug research and development.
-Surfactant: It is used as a surfactant in certain cosmetics and personal care products.
Preparation Method:
The preparation of 3-(2-Hydroxyethyl)pyridine can be carried out by the following steps:
1.2-pyridinecarboxaldehyde and ethylene glycol reaction to generate 2-(2-hydroxyethyl) pyridine.
2.2-(2-hydroxyethyl) pyridine reacts with hydrogen bromide under alkaline conditions to generate 3-(2-Hydroxyethyl)pyridine.
3. Filtration and rectification to obtain pure product.
Safety Information:
- 3-(2-Hydroxyethyl)pyridine is an organic solvent, so care should be taken to avoid open flames to prevent fire.
-Wear appropriate protective equipment such as chemical gloves and safety glasses when in use.
-Avoid skin contact and inhalation of vapors to avoid allergies or other health problems.
-Please make sure to operate in a well-ventilated area when using.
-Immediately after contact with skin or eyes, rinse with plenty of water and seek medical assistance.
Last Update：2024-04-09 20:49:11
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Product Name: 3-(2-Hydroxyethyl)pyridine Visit Supplier Webpage Request for quotation
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