3-(2-chloropyriMidin-4-yl)-1-Methylindole
3-(2-chloropyriMidin-4-yl)-1-Methylindole
CAS: 1032452-86-0
Molecular Formula: C13H10ClN3
3-(2-chloropyriMidin-4-yl)-1-Methylindole - Names and Identifiers
3-(2-chloropyriMidin-4-yl)-1-Methylindole - Physico-chemical Properties
| Molecular Formula | C13H10ClN3 |
| Molar Mass | 243.6916 |
| Density | 1.31±0.1 g/cm3(Predicted) |
| Boling Point | 486.3±28.0 °C(Predicted) |
| pKa | -0.89±0.31(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Use | Uses 3-(2-chloropyrimidin-4-yl)-1-methylindole is used as AZD9291 (ostinib) intermediate. |
3-(2-chloropyriMidin-4-yl)-1-Methylindole - Upstream Downstream Industry
| Downstream Products | N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine AZ 7550 |
3-(2-chloropyriMidin-4-yl)-1-Methylindole - Introduction
3-(2-chloropyriMidin-4-yl)-1-Methylindole, also known as CMI (Chloropyrimidinyl Methyl Indole), is a compound containing chloropyrimidine and methylindole groups.
Nature:
-Appearance: Colorless or light yellow solid
-Molecular formula: C12H10ClN3
-Molecular weight: 235.6801g/mol
-Melting Point: 125-127 ℃
-Boiling point and boiling point: no relevant data available
Use:
- 3-(2-chroopyrimidin-4-yl)-1-Methylindole is an organic compound containing indole and pyrimidine heterocycles. It has many applications in the fields of medicine and pesticides.
-In the field of medicine, the compound is studied as a growth-inhibiting anti-tumor agent and anti-inflammatory agent, and also has antibacterial activity.
-In the field of pesticides, it is studied as an insecticide and herbicide.
Method:
3-(2-choropyrimidin-4-yl)-1-Methylindole can be synthesized by a variety of methods, one of the common methods is the reaction of 2-chloropyrimidine-4-carboxylic acid with 1-methylindole under basic conditions.
Safety Information:
- 3-(2-chloropyriMidin-4-yl)-1-Methylindole has limited toxicity and safety data.
-regular laboratory safety practices should be followed during handling and handling, including wearing appropriate personal protective equipment and avoiding contact with skin and eyes.
-When using or handling this compound, care should be taken to prevent fire and to avoid inhalation, ingestion or contact.
Please note that the use and handling of any chemical substances should follow appropriate safe operating and laboratory regulations, and professionals should be consulted when needed.
Nature:
-Appearance: Colorless or light yellow solid
-Molecular formula: C12H10ClN3
-Molecular weight: 235.6801g/mol
-Melting Point: 125-127 ℃
-Boiling point and boiling point: no relevant data available
Use:
- 3-(2-chroopyrimidin-4-yl)-1-Methylindole is an organic compound containing indole and pyrimidine heterocycles. It has many applications in the fields of medicine and pesticides.
-In the field of medicine, the compound is studied as a growth-inhibiting anti-tumor agent and anti-inflammatory agent, and also has antibacterial activity.
-In the field of pesticides, it is studied as an insecticide and herbicide.
Method:
3-(2-choropyrimidin-4-yl)-1-Methylindole can be synthesized by a variety of methods, one of the common methods is the reaction of 2-chloropyrimidine-4-carboxylic acid with 1-methylindole under basic conditions.
Safety Information:
- 3-(2-chloropyriMidin-4-yl)-1-Methylindole has limited toxicity and safety data.
-regular laboratory safety practices should be followed during handling and handling, including wearing appropriate personal protective equipment and avoiding contact with skin and eyes.
-When using or handling this compound, care should be taken to prevent fire and to avoid inhalation, ingestion or contact.
Please note that the use and handling of any chemical substances should follow appropriate safe operating and laboratory regulations, and professionals should be consulted when needed.
Last Update：2024-04-09 15:18:03
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CAS: 1032452-86-0
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Product Name: 3-(2-chloropyriMidin-4-yl)-1-Methylindole Visit Supplier Webpage Request for quotation
CAS: 1032452-86-0
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