3-(2-methyl-1-piperidyl)propylamine
1-(3-aminopropyl)-2-pipecoline
CAS: 25560-00-3
Molecular Formula: C9H20N2
3-(2-methyl-1-piperidyl)propylamine - Names and Identifiers
| Name | 1-(3-aminopropyl)-2-pipecoline |
| Synonyms | NAPPC N-3-AMINOPROPYL-2-PIRECOLINE 1-(3-aminopropyl)-2-pipecoline N-(3-Aminopropyl)-2-pipecoline 1-Piperidinepropanamine, 2-methyl- 3-(2-methyl-1-piperidyl)propylamine 2,2,6,6-tetramethylpiperidin-4-amine 3-(2-Methyl-1-piperidinyl)propylamine 1-(3-aminopropyl)-2-methyl piperidine 3-(2-methyl-1-piperidyl)propan-1-amine 3-(2-methylpiperidin-1-yl)propan-1-amine |
| CAS | 25560-00-3 |
| EINECS | 247-102-3 |
| InChI | InChI=1/C9H20N2/c1-9-5-2-3-7-11(9)8-4-6-10/h9H,2-8,10H2,1H3 |
3-(2-methyl-1-piperidyl)propylamine - Physico-chemical Properties
| Molecular Formula | C9H20N2 |
| Molar Mass | 156.27 |
| Density | 0.889g/mLat 25°C(lit.) |
| Boling Point | 96-97°C15mm Hg(lit.) |
| Flash Point | 191°F |
| Vapor Presure | 0.191mmHg at 25°C |
| pKa | 10.44±0.10(Predicted) |
| Refractive Index | n20/D 1.4765(lit.) |
3-(2-methyl-1-piperidyl)propylamine - Risk and Safety
| Hazard Symbols | C - Corrosive |
| Risk Codes | 34 - Causes burns |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S27 - Take off immediately all contaminated clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 3267 8/PG 3 |
| WGK Germany | 3 |
| Hazard Class | 8 |
| Packing Group | III |
3-(2-methyl-1-piperidyl)propylamine - Introduction
1-(3-aminopropyl)-2-pipecoline is an organic compound with the chemical formula C9H19N2, and its molecular structure contains a piperidine ring and a 3-aminopropyl side chain.
its physical properties for the colorless liquid, there is a special odor of amine. The compound has high solubility and is soluble in water and many organic solvents.
1-(3-aminoppyl)-2-pipecoline is mainly used in the field of medicine. As a drug raw material acting on the nervous system, it is commonly used in the synthesis of hetero-cyclic nerve preparations. In addition, it can also be used in the preparation of antidepressant drugs, anti-cancer drugs and other aspects of the study.
There are two main methods for preparing 1-(3-aminoppyl)-2-pipecoline. In one, 2-methylpiperidine and propenyl Amine are heated to give the desired product. The other is the reaction of 2-methylpiperidine with acrylonitrile in the presence of a strong base, followed by acidification of the reaction product with acetic acid to give 1-(3-aminopropyl)-2-pipecoline.
Regarding safety information, 1-(3-aminoppyl)-2-pipecoline is generally relatively safe when used and stored correctly. However, it is an irritant and may cause irritation to the eyes, skin and respiratory tract when contacted. Therefore, you should pay attention to wearing appropriate protective equipment when using, avoid direct contact with skin and eyes, and ensure a well-ventilated environment. In addition, the toxicity and carcinogenicity of this compound have not been fully studied, so long-term exposure and excessive exposure should be avoided. Correct laboratory practices should be followed during disposal and waste should be properly disposed.
its physical properties for the colorless liquid, there is a special odor of amine. The compound has high solubility and is soluble in water and many organic solvents.
1-(3-aminoppyl)-2-pipecoline is mainly used in the field of medicine. As a drug raw material acting on the nervous system, it is commonly used in the synthesis of hetero-cyclic nerve preparations. In addition, it can also be used in the preparation of antidepressant drugs, anti-cancer drugs and other aspects of the study.
There are two main methods for preparing 1-(3-aminoppyl)-2-pipecoline. In one, 2-methylpiperidine and propenyl Amine are heated to give the desired product. The other is the reaction of 2-methylpiperidine with acrylonitrile in the presence of a strong base, followed by acidification of the reaction product with acetic acid to give 1-(3-aminopropyl)-2-pipecoline.
Regarding safety information, 1-(3-aminoppyl)-2-pipecoline is generally relatively safe when used and stored correctly. However, it is an irritant and may cause irritation to the eyes, skin and respiratory tract when contacted. Therefore, you should pay attention to wearing appropriate protective equipment when using, avoid direct contact with skin and eyes, and ensure a well-ventilated environment. In addition, the toxicity and carcinogenicity of this compound have not been fully studied, so long-term exposure and excessive exposure should be avoided. Correct laboratory practices should be followed during disposal and waste should be properly disposed.
Last Update：2024-04-09 20:52:54
