3-(3,6-Dibromo-9H-carbazol-9-yl)-N,N-dimethyl-2-hydroxypropylamine
1-(3,6-DIBROMO-9H-CARBAZOL-9-YL)-3-(DIMETHYLAMINO)PROPAN-2-OL
CAS: 253449-04-6
Molecular Formula: C17H18Br2N2O
3-(3,6-Dibromo-9H-carbazol-9-yl)-N,N-dimethyl-2-hydroxypropylamine - Names and Identifiers
3-(3,6-Dibromo-9H-carbazol-9-yl)-N,N-dimethyl-2-hydroxypropylamine - Physico-chemical Properties
| Molecular Formula | C17H18Br2N2O |
| Molar Mass | 426.15 |
| Density | 1.62±0.1 g/cm3(Predicted) |
| Melting Point | 153-155 |
| Boling Point | 320.2±22.0 °C(Predicted) |
| Solubility | DMSO: soluble10mg/mL, clear |
| Appearance | White solid |
| Color | white to beige |
| pKa | 14.40±0.20(Predicted) |
| Storage Condition | 2-8°C |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months. |
| Use | Use A selective N-wasp inhibitor. Wiskostatin is a selective inhibitor of N-WASP, a ubiquitously expressed member of the Wiskott-Aldrich Syndrome protein (WASp) family that regulates actin polymerization. Wiskostatin inhibits actin-dependent cellular functions, including migration, transmembrane transport and phagocytosis. |
3-(3,6-Dibromo-9H-carbazol-9-yl)-N,N-dimethyl-2-hydroxypropylamine - Risk and Safety
| Risk Codes | 25 - Toxic if swallowed |
| Safety Description | 45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 2811 6.1 / PGIII |
| WGK Germany | 3 |
| Hazard Note | Irritant |
| Hazard Class | 6.1 |
3-(3,6-Dibromo-9H-carbazol-9-yl)-N,N-dimethyl-2-hydroxypropylamine - Introduction
1-(3,-)-3-(DIMETHYLAMINO)PROPAN-2-OL(1-(3,6-dibromo-9-carbazol-9-yl)-3-(DIMETHYLAMINO) propanol) is an organic compound. The following is a description of the properties, uses, preparation and safety information of 1-(3,)-3-(DIMETHYLAMINO)PROPAN-2-OL:
Properties: 1-(3, -3)-3-(DIMETHYLAMINO)PROPAN-2-OL is a solid compound with a white to pale yellow color. It has moderate solubility and is soluble in organic solvents such as dimethyl sulfoxide and methylene chloride. The 1-(3, -3)-3-(DIMETHYLAMINO)PROPAN-2-OL is stable at room temperature.
use: 1-(3,-)-3-(DIMETHYLAMINO)PROPAN-2-OL is a broad-spectrum alcohol (ADE) inhibitor. It has important application potential in the field of biomedicine, especially in cancer treatment. The 1-(3, -3)-3-(DIMETHYLAMINO)PROPAN-2-OL can inhibit the activity of ADE, thereby inhibiting cell proliferation and tumor growth.
Preparation method: The preparation method of 1-(3, 1)-3-(DIMETHYLAMINO)PROPAN-2-OL is relatively complicated. The general synthetic route is to react 3,6-dibromo-9H-carbazole with N,N-dimethyl-N-(3-carboxypropyl)-2-bromoacetamide to form the intermediate. The intermediate is then reacted with dimethylaminopropanol to give the final product 1-(3, dimethyl)-3-(DIMETHYLAMINO)PROPAN-2-OL.
Safety information: The safety research on 1-(3, -3)-3-(DIMETHYLAMINO)PROPAN-2-OL is relatively limited, so it needs to be handled with caution when using it. The substance may be irritating and harmful to the skin, eyes and respiratory tract. Wear appropriate personal protective equipment such as chemical goggles, gloves and protective clothing during operation. It is recommended to use in a well-ventilated area and to avoid inhalation or ingestion of 1-(3, -3)-3-(DIMETHYLAMINO)PROPAN-2-OL. If necessary, follow appropriate laboratory practices and safe operating instructions.
Properties: 1-(3, -3)-3-(DIMETHYLAMINO)PROPAN-2-OL is a solid compound with a white to pale yellow color. It has moderate solubility and is soluble in organic solvents such as dimethyl sulfoxide and methylene chloride. The 1-(3, -3)-3-(DIMETHYLAMINO)PROPAN-2-OL is stable at room temperature.
use: 1-(3,-)-3-(DIMETHYLAMINO)PROPAN-2-OL is a broad-spectrum alcohol (ADE) inhibitor. It has important application potential in the field of biomedicine, especially in cancer treatment. The 1-(3, -3)-3-(DIMETHYLAMINO)PROPAN-2-OL can inhibit the activity of ADE, thereby inhibiting cell proliferation and tumor growth.
Preparation method: The preparation method of 1-(3, 1)-3-(DIMETHYLAMINO)PROPAN-2-OL is relatively complicated. The general synthetic route is to react 3,6-dibromo-9H-carbazole with N,N-dimethyl-N-(3-carboxypropyl)-2-bromoacetamide to form the intermediate. The intermediate is then reacted with dimethylaminopropanol to give the final product 1-(3, dimethyl)-3-(DIMETHYLAMINO)PROPAN-2-OL.
Safety information: The safety research on 1-(3, -3)-3-(DIMETHYLAMINO)PROPAN-2-OL is relatively limited, so it needs to be handled with caution when using it. The substance may be irritating and harmful to the skin, eyes and respiratory tract. Wear appropriate personal protective equipment such as chemical goggles, gloves and protective clothing during operation. It is recommended to use in a well-ventilated area and to avoid inhalation or ingestion of 1-(3, -3)-3-(DIMETHYLAMINO)PROPAN-2-OL. If necessary, follow appropriate laboratory practices and safe operating instructions.
Last Update：2024-04-09 20:49:11
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