3-(3-BROMOPHENYL)-BETA-ALANINE

3-(3-BROMOPHENYL)-BETA-ALANINE - Names and Identifiers

Name	DL-beta-(3-Bromophenyl)alanine
Synonyms	BIO-FARMA BF000138 RARECHEM AK HC T307 DL--(3-Bromophenyl)alanine DL-BETA-(3-BROMOPHENYL)ALANINE DL-beta-(3-Bromophenyl)alanine 3-(3-BROMOPHENYL)-BETA-ALANINE 3-(3-BROMOPHENYL)-DL-BETA-ALANINE Benzenepropanoic acid, β-amino-3-bromo- 3-AMINO-3-(3-BROMOPHENYL)PROPANOIC ACID 3-AMINO-3-(3-BROMO-PHENYL)-PROPIONIC ACID Benzenepropanoic acid, .beta.-amino-3-bromo- (3S)-3-amino-3-(3-bromophenyl)propanoic acid DL-3-AMINO-3-(3-BROMO-PHENYL)-PROPIONIC ACID (3R)-3-amino-3-(3-bromophenyl)propanoic acid
CAS	117391-50-1
InChI	InChI=1/C9H10BrNO2/c10-7-3-1-2-6(4-7)8(11)5-9(12)13/h1-4,8H,5,11H2,(H,12,13)/t8-/m0/s1

3-(3-BROMOPHENYL)-BETA-ALANINE - Physico-chemical Properties

Molecular Formula	C9H10BrNO2
Molar Mass	244.09
Density	1.585±0.06 g/cm3(Predicted)
Melting Point	227 °C (dec.) (lit.)
Boling Point	367.3±32.0 °C(Predicted)
Flash Point	176°C
Vapor Presure	4.83E-06mmHg at 25°C
Appearance	White powder
pKa	3.60±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Refractive Index	1.607
MDL	MFCD00995843
Physical and Chemical Properties	WGK Germany:3

3-(3-BROMOPHENYL)-BETA-ALANINE - Risk and Safety

WGK Germany

3-(3-BROMOPHENYL)-BETA-ALANINE - Reference Information

use

3-amino -3-(3-bromophenyl) propionic acid is a carboxylic acid Derivatives can be used as intermediates in pharmaceutical synthesis, used in pharmaceutical synthesis and pharmaceutical experimental research.

preparation

add 28.129(0.2mol)3-bromobenzaldehyde, 29.129(0.28mol) malonic acid, 3.3mL piperidine and 120mL ethanol into an autoclave with a volume of 500mL, tighten the autoclave, check the air tightness, and replace the air in the autoclave with nitrogen. When the pressure rises to 0.6~0.8

MPa, start heating and stirring. The reaction temperature was controlled at 95 ℃ for 10h. The pressure will gradually increase at the beginning of the reaction, and the pressure will decrease at the end of the reaction. When the pressure of the autoclave is unchanged, the reaction is stopped, the reaction mixture is cooled to room temperature, and the filtration is carried out. Wash the solid with 50mL distilled water and dry it to obtain 31.69 white powder product.

Last Update：2024-04-09 15:16:38