3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE)-PYRAZOLE

3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE)-PYRAZOLE - Names and Identifiers

Name	1H-Pyrazole-3-boronic acid pinacol ester
Synonyms	Pyrazole-3-boronic acid pinacol ester PYRAZOLE-3-BORONIC ACID PINACOL ESTER 1H-Pyrazole-3-boronic acid pinacol ester 1H-Pyrazole-5-boronic acid pinacol ester 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOLONE)-PYRAZOLE 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOLONE)-PYRRAZOLE 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxabolone)-Pyrrazole 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane)-Pyrazole 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE)-PYRAZOLE 3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE-2-YL)PYRRAZOLE 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole 3-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-1H-PYRAZOLE 1H-pyrazole, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- 1H-pyrazole, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
CAS	844501-71-9 1086111-17-2
InChI	InChI=1/C9H15BN2O2/c1-8(2)9(3,4)14-10(13-8)7-5-6-11-12-7/h5-6H,1-4H3,(H,11,12)

3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE)-PYRAZOLE - Physico-chemical Properties

Molecular Formula	C9H15BN2O2
Molar Mass	194.04
Density	1.09±0.1 g/cm3(Predicted)
Melting Point	105-108°C
Boling Point	335.4±15.0 °C(Predicted)
Flash Point	156.628°C
Water Solubility	Insoluble in water.
Vapor Presure	0mmHg at 25°C
pKa	14.02±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.487
MDL	MFCD07368044

3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE)-PYRAZOLE - Risk and Safety

Hazard Symbols	T - Toxic
Risk Codes	R25 - Toxic if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S37 - Wear suitable gloves. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
UN IDs	UN2811
HS Code	29331990

3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLANE)-PYRAZOLE - Introduction

1H-Pyrazole-3-boronic acid pinacol ester is an organic compound with the chemical formula C11H15BN2O2. It is a white crystalline solid with a molecular weight of 216.06g/mol.

1H-Pyrazole-3-boronic acid pinacol ester has a wide range of uses. It is an important organic synthesis intermediate and can be used to synthesize various compounds containing pyrazole structures. In the field of medicine, it is used to synthesize drugs and drug candidate compounds, such as anticancer drugs, bioactive substances and fluorescent probes. In addition, 1H-Pyrazole-3-boronic acid pinacol ester is also used in the synthesis of pesticides and other fields.

The method for preparing 1H-Pyrazole-3-boronic acid pinacol ester is usually through esterification. A commonly used synthetic method is the reaction of substituted 1H-pyrazole-3-boronic acids with pinacol for esterification under acid-catalyzed conditions to give 1H-Pyrazole-3-boronic acid pinacol ester products.

Regarding safety information, 1H-Pyrazole-3-boronic acid pinacol ester may be irritating to the human body, so it is necessary to take corresponding protective measures during use to avoid direct contact with skin and eyes. During storage and handling, avoid contact with oxidants, acids and strong oxidants to prevent dangerous reactions. In addition, it needs to be stored properly and kept away from high temperatures, ignition sources and open flames.

Last Update：2024-04-09 20:52:54