3-(4-Fluorophenylethylamino)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
IM-12
CAS: 1129669-05-1
Molecular Formula: C22H20FN3O2
3-(4-Fluorophenylethylamino)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione - Names and Identifiers
3-(4-Fluorophenylethylamino)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione - Physico-chemical Properties
| Molecular Formula | C22H20FN3O2 |
| Molar Mass | 377.41 |
| Density | 1.34±0.1 g/cm3(Predicted) |
| Melting Point | 187 °C |
| Boling Point | 600.2±55.0 °C(Predicted) |
| Solubility | DMSO: ≥ 54.9 mg/mL |
| Appearance | powder |
| Color | yellow-orange |
| pKa | 16.77±0.30(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| In vitro study | In hNPCs, IM-12 inhibited GSK-3β activity with an IC50 of 3.8 μm, followed by a significant increase in β-catenin concentration. Through the activation of conventional Wnt signaling pathway, IM-12 promote the proliferation of human neural progenitor cells. |
3-(4-Fluorophenylethylamino)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| WGK Germany | 3 |
3-(4-Fluorophenylethylamino)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.65 ml | 13.248 ml | 26.496 ml |
| 5 mM | 0.53 ml | 2.65 ml | 5.299 ml |
| 10 mM | 0.265 ml | 1.325 ml | 2.65 ml |
| 5 mM | 0.053 ml | 0.265 ml | 0.53 ml |
Last Update：2024-01-02 23:10:35
3-(4-Fluorophenylethylamino)-1-methyl-4-(2-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione - Introduction
IM-12 is a metal organic framework (MOF) with many unique properties. The IM-12 structure is composed of metal ions or metal clusters and organic ligands, forming a three-dimensional porous crystal structure.
IM-12 have highly adjustable pore structure and surface area, which can be used for gas adsorption, gas separation, catalytic reaction and other applications. Due to its large number of Microporous and mesoporous structures, IM-12 can be used to store and release gases, such as hydrogen storage, natural gas reserves, etc. In addition, IM-12 can also be used in catalytic reactions, such as organic synthesis and degradation of environmental pollutants.
The preparation of IM-12 is generally achieved by solvothermal synthesis. Generally, a metal ion or metal cluster and an organic ligand are dissolved in an organic solvent, and then crystals are formed by heating the reaction vessel for an appropriate time and temperature.
When using IM-12, you need to pay attention to some safety information. IM-12 is relatively stable under normal conditions, but may decompose under high temperature or strong acid-base conditions. Therefore, in laboratory operations, care should be taken to avoid high temperatures and strong acid-base environments. In addition, the synthesis of IM-12 involves the use of organic solvents and chemicals, and it is necessary to pay attention to the relevant safety practices, such as wearing appropriate personal protective equipment and maintaining good ventilation.
IM-12 have highly adjustable pore structure and surface area, which can be used for gas adsorption, gas separation, catalytic reaction and other applications. Due to its large number of Microporous and mesoporous structures, IM-12 can be used to store and release gases, such as hydrogen storage, natural gas reserves, etc. In addition, IM-12 can also be used in catalytic reactions, such as organic synthesis and degradation of environmental pollutants.
The preparation of IM-12 is generally achieved by solvothermal synthesis. Generally, a metal ion or metal cluster and an organic ligand are dissolved in an organic solvent, and then crystals are formed by heating the reaction vessel for an appropriate time and temperature.
When using IM-12, you need to pay attention to some safety information. IM-12 is relatively stable under normal conditions, but may decompose under high temperature or strong acid-base conditions. Therefore, in laboratory operations, care should be taken to avoid high temperatures and strong acid-base environments. In addition, the synthesis of IM-12 involves the use of organic solvents and chemicals, and it is necessary to pay attention to the relevant safety practices, such as wearing appropriate personal protective equipment and maintaining good ventilation.
Last Update：2024-04-09 21:04:16
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Product Name: IM-12 Visit Supplier Webpage Request for quotation
CAS: 1129669-05-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 1129669-05-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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