3-(Benzyloxy)piperidine - Names and Identifiers
3-(Benzyloxy)piperidine - Physico-chemical Properties
Molecular Formula | C12H17NO
|
Molar Mass | 191.27 |
Density | 1.03±0.1 g/cm3(Predicted) |
Boling Point | 288.3±33.0 °C(Predicted) |
Flash Point | 116.7°C |
Vapor Presure | 0.00236mmHg at 25°C |
pKa | 9.37±0.10(Predicted) |
Storage Condition | Room Temprature |
Refractive Index | 1.539 |
3-(Benzyloxy)piperidine - Introduction
3-(benzyloxy)piperidine is an organic compound whose chemical formula is C12H17NO. The following is a detailed description of the nature, use, method and safety information of 3-(benzyloxy)piperidine:
Nature:
- 3-(benzyloxy)piperidine is a colorless liquid with a special smell.
-Its melting point is -5°C and boiling point is 245°C.
- 3-(benzyloxy)piperidine can be dissolved in many organic solvents, such as ethanol, dimethyl sulfoxide and acetonitrile under normal temperature and pressure.
Use:
- 3-(benzyloxy)piperidine are widely used as intermediates in organic chemical synthesis.
-It can be used to prepare compounds such as drugs and pesticides, and has important applications in the fields of medicinal chemistry, medicine and agriculture.
Preparation Method:
- 3-(benzyloxy)piperidine has many preparation methods. The following is a commonly used synthetic route:
1. Benzyl alcohol is reacted with benzyl magnesium bromide to obtain benzyl alcohol.
2. Benzyl alcohol and piperidine are heated to react in the presence of cuprous chloride to generate 3-(benzyloxy)piperidine.
Safety Information:
- 3-(benzyloxy)piperidine can enter the body through inhalation, skin contact and ingestion.
-It may cause irritation to the central nervous system, eyes and skin.
-When handling 3-(benzyloxy)piperidine, it is necessary to take appropriate protective measures, including wearing protective glasses, gloves and protective clothing.
-During use and storage, pay attention to avoid contact with oxidants and strong acids to prevent dangerous reactions.
Last Update:2024-04-09 02:00:45