3-(Bromoacetyl)benzothiophene

3-(Bromoacetyl)benzothiophene - Names and Identifiers

Name	1-benzo[b]thiophen-3-yl-2-bromoethan-1-one
Synonyms	3-(Bromoacetyl)benzothiophene 3-(Bromoacetyl)benzo[b]thiophene 1-(1-benzothiophen-3-yl)-2-bromoethanone 1-benzo[b]thiophen-3-yl-2-bromoethan-1-one 1-BENZO[B]THIOPHEN-3-YL-2-BROMOETHAN-1-ONE 1-(1-BENZOTHIOPHEN-3-YL)-2-BROMO-1-ETHANONE
CAS	26167-45-3
InChI	InChI=1/C10H7BrOS/c11-5-9(12)8-6-13-10-4-2-1-3-7(8)10/h1-4,6H,5H2

3-(Bromoacetyl)benzothiophene - Physico-chemical Properties

Molecular Formula	C10H7BrOS
Molar Mass	255.13
Density	1.617g/cm³
Melting Point	138 °C
Boling Point	352°C at 760 mmHg
Flash Point	166.7°C
Vapor Presure	3.96E-05mmHg at 25°C
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.689

3-(Bromoacetyl)benzothiophene - Risk and Safety

Hazard Symbols	C - Corrosive
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R34 - Causes burns
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S26/37/39 -
UN IDs	3261
HS Code	29349990
Hazard Note	Corrosive
Hazard Class	IRRITANT

3-(Bromoacetyl)benzothiophene - Introduction

1-benzo [B] thiophen-3-yl-2-bromoethan-1-one is an organic compound with the chemical formula C12H8BrOS. The following is a detailed description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: 1-benzo [B] thiophen-3-yl-2-bromoethan-1-one is a solid substance, showing white to light yellow crystal particles at room temperature.
-Melting point: The melting point of the compound is about 80-82 degrees Celsius.
-Solubility: It has certain solubility in some organic solvents such as ethanol, dimethyl sulfoxide and chloroform.

Use:
1-benzo [B] thiophen-3-yl-2-bromoethan-1-one are commonly used in organic synthesis reactions and can be used as important intermediates or reagents. It has a wide range of applications in drug synthesis, natural product synthesis and organic chemical reactions.

Method:
1-benzo [B] thiophen-3-yl-2-bromoethan-1-one can be synthesized by the following steps:
1. 1-benzo [B] thiophene and bromoacetic acid are reacted to obtain 1-benzo [B] thiophen-3-yl-2-bromoacetic acid.
2. 1-benzo [B] thiophen-3-yl-2-bromoacetic acid is converted into 1-benzo [B] thiophen-3-yl-2-bromoethan-1-one by reacting with sodium carbonate under alkaline conditions.

Safety Information:
-Since there is no specific safety information to provide, when using chemicals, be sure to follow the correct laboratory operating procedures and wear appropriate personal protective equipment, avoid direct contact with skin and eyes, and use in a well-ventilated area.

Last Update：2024-04-09 21:04:16